Active Recombinant Human CXCL3

• Cat.No.: CXCL3-18H
• Product Overview: Human recombinant MIP-2 beta is produced in genetically engineered yeast, and purified by sequential chromatography.

Specification

• Species: Human
• Source: yeast
• Tag: Non
• Description: This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils.
• Form: In 0.1M ammonium acetate at a concentration of 0.50 mg protein/ml
• Bio-activity: The biological activity of recombinant human MIP-2 beta is determined by its use as a cofactor for CSF-dependent myelopoiesis.
• Purity: Over 95% pure by SDS gel electrophoresis, with low level of endotoxin.
• Stability: Several months at -80°C.
• Storage: Store at -80°C.

Gene Information

• Gene Name: CXCL3?chemokine (C-X-C motif) ligand 3 [?Homo sapiens?(human) ]
• Official Symbol: CXCL3
• Synonyms: GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b; GRO-gamma; GRO-gamma(1-73); MIP2-beta; SCYB3; C-X-C motif chemokine 3; GRO3 oncogene; Growth-regulated protein gamma; MGSA gamma; chemokine (C-X-C motif) ligand 3; melanoma growth stimulatory activity gamma; Macrophage inflammatory protein 2-beta [Precursor]; MIP2B_HUMAN; CXCL3
• Gene ID: 2921
• mRNA Refseq: NM_002090
• Protein Refseq: NP_002081
• MIM: 139111
• UniProt ID: P19876
• Chromosome Location: 4q21
• Pathway: Chemokine receptors bind chemokines; Chemokine signaling pathway; G alpha (i) signalling events
• Function: CXCR chemokine receptor binding; chemokine activity