Active Recombinant Human CXCL6 protein

Cat.No. : CXCL6-171H
Product Overview : Recombinant Human CXCL6 protein was expressed in CHO.
  • Specification
  • Gene Information
  • Related Products
Description : Granulocyte chemotactic protein 2 (GCP-2) also known as Chemokine (C-X-C motif) ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. As its former name suggests, GCP-2 is a chemoattractant for neutrophilic granulocytes. Among human CXC chemokines, GCP­2 is most closely related to ENA­78 (78% amino acid (aa) sequence identity in the mature peptide region and 86% identity in the signal sequence). The structure and sequence of the genes for human GCP­2 and ENA­78 also exhibit close similarity suggesting the two genes may have originated from a gene duplication. GCP­2 can signal through the CXCR1 and CXCR2 receptors.
Source : CHO
Species : Human
Form : Lyophilized after extensive dialysis against PBS.
Bio-activity : The EC50 value of human GCP-2/CXCL6 on Ca2+ mobilization assay in CHO-K1/ Gα15/hCXCR2 cells (human Gα15 and human CXCR2 stably expressed in CHO-K1 cells) is less than 0.8 μg/ml.
Molecular Mass : ~9 kDa
Endotoxin : < 0.2 EU/μg of protein by gel clotting method.
Purity : > 98%
Storage : Upon receiving, this product remains stable for up to 6 months at lower than -70 centigrade. Upon reconstitution, the product should be stable for up to 1 week at 4 centigrade or up to 3 months at -20 centigrade. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.
Gene Name : CXCL6 C-X-C motif chemokine ligand 6 [ Homo sapiens (human) ]
Official Symbol : CXCL6
Synonyms : CXCL-6; SCYB6; GCP-2; CKA-3
Gene ID : 6372
mRNA Refseq : NM_002993.4
Protein Refseq : NP_002984.1
MIM : 138965
UniProt ID : P80162

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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