Active Recombinant Human EREG Protein

• Cat.No.: EREG-023H
• Product Overview: The mature recombinant human Epiregulin protein containing 46aa (V63-L108) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 63-108 a.a.
• Description: This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.
• Bio-activity: Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.125-0.75 ng/mL.
• Molecular Mass: 5.4 kDa
• Product-Related Proteins: 63-108
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: EREG epiregulin [ Homo sapiens (human) ]
• Official Symbol: EREG
• Synonyms: EREG; epiregulin; ER; Ep; EPR; proepiregulin
• Gene ID: 2069
• mRNA Refseq: NM_001432
• Protein Refseq: NP_001423
• MIM: 602061
• UniProt ID: O14944