Active Recombinant Human EREG Protein
Cat.No. : | EREG-004H |
Product Overview : | The mature recombinant human Ang-2 protein containing 478aa (Y19-F496) without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Measured by its ability to activate Tie-2 in C6 rat glial cells transfected with human Tie-2. 0.2 μg/mL of Recombinant Human Angiopoietin-2 significantly induces phosphorylation of human Tie-2. |
Molecular Mass : | 56 kDa |
Product-Related Proteins : | 19-496 |
Endotoxin : | < 0.1 EU/μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | At -80 centigrade. Avoid repeated freeze-thaw cycles. |
Gene Name : | ANGPT2 angiopoietin 2 [ Homo sapiens (human) ] |
Official Symbol : | EREG |
Synonyms : | ANGPT2; angiopoietin 2; ANG2; AGPT2; LMPHM10; angiopoietin-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a |
Gene ID : | 285 |
mRNA Refseq : | NM_001147 |
Protein Refseq : | NP_001138 |
MIM : | 601922 |
UniProt ID : | O15123 |
Products Types
◆ Recombinant Protein | ||
EREG-562H | Active Recombinant Human EREG protein(Val63-Leu108), hFc-tagged | +Inquiry |
EREG-125E | Active Recombinant Human EREG Protein (50 aa) | +Inquiry |
EREG-3465H | Recombinant Human EREG Protein, GST-tagged | +Inquiry |
EREG-023H | Active Recombinant Human EREG Protein | +Inquiry |
EREG-1438H | Recombinant Human EREG Protein, His-tagged | +Inquiry |
◆ Lysates | ||
EREG-1868HCL | Recombinant Human EREG cell lysate | +Inquiry |
EREG-1871MCL | Recombinant Mouse EREG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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