Active Recombinant Human EZH2 Complex protein, His/Flag-tagged
Cat.No. : | EZH2-3948H |
Product Overview : | Recombinant human EZH2 (accession number NM_004456, amino acids 2-end with an N-terminal His tag, molecular weight 86 kDa) was coexpressed in a baculovirus ex |
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Source : | Insect cells |
Species : | Human |
Tag : | His&Flag |
Form : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl and 20% glycerol. |
Bio-activity : | 0.08 pmol/min/μg. |
Applications : | Recombinant EZH2 protein complex is suitable for use in histone methyltransferase assays. |
Stability : | This product is guaranteed for 6 months from date of receipt. |
Storage : | Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
Concentration : | 0.57 µg/µl |
Protein length : | 2-end |
Gene Name : | EZH2 enhancer of zeste homolog 2 (Drosophila) [ Homo sapiens ] |
Official Symbol : | EZH2 |
Synonyms : | EZH2; enhancer of zeste homolog 2 (Drosophila); enhancer of zeste (Drosophila) homolog 2; histone-lysine N-methyltransferase EZH2; ENX 1; EZH1; KMT6; KMT6A; lysine N-methyltransferase 6; ENX1; WVS2; ENX-1; MGC9169; |
Gene ID : | 2146 |
mRNA Refseq : | NM_004456 |
Protein Refseq : | NP_004447 |
MIM : | 601573 |
UniProt ID : | Q15910 |
Chromosome Location : | 7q35-q36 |
Function : | DNA binding; histone methyltransferase activity; histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transferase activity; |
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◆ Lysates | ||
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◆ Assay kits | ||
Kit-1725 | EZH2 (Y641N) Chemiluminescent Assay Kit | +Inquiry |
Kit-1724 | EZH2 (Y641F) Chemiluminescent Assay Kit | +Inquiry |
Kit-1726 | EZH2 Chemiluminescent Assay Kit | +Inquiry |
Kit-1723 | EZH2 (A677G) Chemiluminescent Assay Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe versatility of the EZH2 protein is truly remarkable, as it can be employed across a wide range of applications in my research.
In addition to its outstanding quality, the manufacturer of the EZH2 protein offers excellent technical support that can effectively address any challenges I may encounter.
Their dedicated team of experts is readily available to provide guidance and assistance, ensuring a seamless integration of the EZH2 protein into my experimental setup.
Q&As (5)
Ask a questionEZH2 overexpression is associated with promoting tumor cell proliferation, invasion, and metastasis, leading to cancer progression.
EZH2 has been implicated in various non-oncological conditions, including cardiovascular diseases and neurodegenerative disorders.
Potential side effects may include hematological toxicity, gastrointestinal issues, and liver enzyme elevation.
Small molecule inhibitors of EZH2 have been developed and are being investigated as potential cancer therapies.
High EZH2 expression has been associated with poor prognosis in several cancer types.
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