Recombinant Human EZH2 293 Cell Lysate
Cat.No. : | EZH2-6487HCL |
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Description : | Antigen standard for enhancer of zeste homolog 2 (Drosophila) (EZH2), transcript variant 1 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Tag : | Non |
Gene Name : | EZH2 enhancer of zeste homolog 2 (Drosophila) [ Homo sapiens ] |
Official Symbol : | EZH2 |
Synonyms : | EZH2; enhancer of zeste homolog 2 (Drosophila); enhancer of zeste (Drosophila) homolog 2; histone-lysine N-methyltransferase EZH2; ENX 1; EZH1; KMT6; KMT6A; lysine N-methyltransferase 6; ENX1; WVS2; ENX-1; MGC9169; |
Gene ID : | 2146 |
mRNA Refseq : | NM_001203247 |
Protein Refseq : | NP_001190176 |
MIM : | 601573 |
UniProt ID : | Q15910 |
Chromosome Location : | 7q35-q36 |
Function : | DNA binding; histone methyltransferase activity; histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
EZH2-285H | Recombinant Human EZH2 Protein, GST-tagged | +Inquiry |
EZH2-1353R | Recombinant Rhesus Macaque EZH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
EZH2-879H | Recombinant Human EZH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
EZH2-5744H | Recombinant Human EZH2 protein, His-tagged | +Inquiry |
EZH2-46H | Recombinant Human EZH2 Protein, His-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1723 | EZH2 (A677G) Chemiluminescent Assay Kit | +Inquiry |
Kit-1725 | EZH2 (Y641N) Chemiluminescent Assay Kit | +Inquiry |
Kit-1727 | EZH2 Homogeneous Assay Kit | +Inquiry |
Kit-1724 | EZH2 (Y641F) Chemiluminescent Assay Kit | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThe versatility of the EZH2 protein is truly remarkable, as it can be employed across a wide range of applications in my research.
In addition to its outstanding quality, the manufacturer of the EZH2 protein offers excellent technical support that can effectively address any challenges I may encounter.
Their dedicated team of experts is readily available to provide guidance and assistance, ensuring a seamless integration of the EZH2 protein into my experimental setup.
Q&As (5)
Ask a questionEZH2 overexpression is associated with promoting tumor cell proliferation, invasion, and metastasis, leading to cancer progression.
EZH2 has been implicated in various non-oncological conditions, including cardiovascular diseases and neurodegenerative disorders.
Potential side effects may include hematological toxicity, gastrointestinal issues, and liver enzyme elevation.
Small molecule inhibitors of EZH2 have been developed and are being investigated as potential cancer therapies.
High EZH2 expression has been associated with poor prognosis in several cancer types.
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