Active Recombinant Human FAP protein, His-tagged
Cat.No. : | FAP-427H |
Product Overview : | Recombinant Human FAP(Leu26-Asp760) fused with His tag at N-terminal was expressed in Insect cells. |
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Source : | Insect cells |
Species : | Human |
Tag : | His |
Form : | Supplied as a 0.2 μm filtered solution in Tris, NaCl and Glycerol. See Certificate of Analysis for details. |
Bio-activity : | Measured by its ability to convert the substrate benzyloxycarbonylGlyPro7amido4methylcoumarin (ZGPAMC) to ZGlyPro and 7amino4methylcoumarin (AMC). The specific activity is >1800 pmol/min/μg, as measured under the described conditions. |
Molecular Mass : | Predicted Molecular Mass: 86 kDa;SDSPAGE: 85 kDa, reducing conditions |
Protein length : | Leu26-Asp760 |
Endotoxin : | <1.0 eu per 1 μg of the protein by the lal>1.0> |
Purity : | >95%, by SDSPAGE under reducing conditions and visualized by silver stain. |
Storage : | Use a manual defrost freezer and avoid repeated freezethaw cycles.6 months from date of receipt, -70 centigrade as supplied.3 months, -70 centigrade under sterile conditions after opening. |
Shipping : | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
Gene Name : | FAP fibroblast activation protein, alpha [ Homo sapiens ] |
Official Symbol : | FAP |
Synonyms : | FAP; fibroblast activation protein, alpha; seprase; DPPIV; integral membrane serine protease; 170 kDa melanoma membrane-bound gelatinase; FAPA; DKFZp686G13158; |
Gene ID : | 2191 |
mRNA Refseq : | NM_004460 |
Protein Refseq : | NP_004451 |
MIM : | 600403 |
UniProt ID : | Q12884 |
Chromosome Location : | 2q23 |
Function : | dipeptidyl-peptidase activity; endopeptidase activity; metalloendopeptidase activity; peptidase activity; protease binding; protein binding; protein dimerization activity; protein homodimerization activity; serine-type endopeptidase activity; serine-type peptidase activity; contributes_to serine-type peptidase activity; serine-type peptidase activity; |
Products Types
◆ Recombinant Protein | ||
FAP-006H | Active Recombinant Human FAP Protein, His-tagged | +Inquiry |
Fap-01M | Active Recombinant Mouse Fap Protein | +Inquiry |
FAP-715H | Recombinant Human FAP Protein, His-tagged | +Inquiry |
FAP-891H | Recombinant Human FAP Protein, His (Fc)-Avi-tagged | +Inquiry |
Fap-716M | Recombinant Mouse Fap Protein, His-tagged | +Inquiry |
◆ Lysates | ||
FAP-1881HCL | Recombinant Human FAP cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1729 | FAP Assay Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewIt enables accurate detection and quantification of FAP protein levels in samples, providing crucial insights into its expression, regulation, and potential functional changes under different experimental conditions.
FAP protein is highly recommended for researchers due to its excellent performance in various assays, particularly in Western blotting (WB) experiments, and its applicability in protein electron microscopy structure analysis.
FAP protein is highly recommended for researchers, as it demonstrates excellent performance in WB experiments and has proven useful in protein electron microscopy structure analysis.
Q&As (5)
Ask a questionFAP can suppress the immune response by modulating the activity of certain immune cells, creating an immunosuppressive tumor microenvironment.
High levels of FAP expression in tumors have been associated with poor prognosis, making it a potential prognostic marker for certain cancers.
Yes, several clinical trials are investigating the safety and efficacy of FAP-targeted therapies in various cancer types.
FAP-targeted therapies are being explored for conditions such as fibrotic diseases and rheumatoid arthritis, extending its potential clinical applications.
Molecular imaging techniques, such as positron emission tomography (PET), can be employed to visualize FAP expression in tumors noninvasively.
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