Active Recombinant Human FGFR4 protein, hFc&His-tagged
Cat.No. : | FGFR4-2660H |
Product Overview : | Active Recombinant Human FGFR-4/CD334 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu22-Asp369) of human FGFR4/FGF Receptor 4 (Accession #NP_998812.1) fused with an Fc, 6×His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | hFc&His |
Form : | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
Bio-activity : | 1.Measured by its binding ability in a functional ELISA. Immobilized recombinant human FGF2 at 1 μg/mL (100 μL/well) can bind recombinant human FGFR4 with a linear range of 30-125 ng/mL. 2.Measured by its binding ability in a functional ELISA. Immobilized recombinant human FGFR4 at 5 μg/mL (100 μL/well) can bind recombinant human FGF12 with a linear range of 35-100 ng/mL. 3.Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.03-0.12 ng/mL. |
Molecular Mass : | 90-110 kDa |
Protein Length : | Leu22-Asp369 |
Endotoxin : | < 0.1 EU/μg of the protein by LAL method. |
Purity : | > 95% by SDS-PAGE. |
Storage : | Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. |
Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. |
Gene Name : | FGFR4 fibroblast growth factor receptor 4 [ Homo sapiens ] |
Official Symbol : | FGFR4 |
Synonyms : | FGFR4; fibroblast growth factor receptor 4; CD334; JTK2; FGFR-4; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; tyrosine kinase related to fibroblast growth factor receptor; TKF; MGC20292; |
Gene ID : | 2264 |
mRNA Refseq : | NM_002011 |
Protein Refseq : | NP_002002 |
MIM : | 134935 |
UniProt ID : | P22455 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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