Recombinant Human FGFR4 protein, hFc-tagged
Cat.No. : | FGFR4-141H |
Product Overview : | Human FGFR4 Protein is expressed from mammalian with a Fc tag at the C-terminal. It contains Leu22-Asp369. |
- Specification
- Gene Information
- Related Products
Description : | Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. |
Source : | HEK293 |
Species : | Human |
Tag : | hFc |
Form : | Supplied as 0. 22um filtered solution in PBS (pH 7. 4). |
Molecular Mass : | The protein has a predicted MW of 65. 3 kDa. Due to glycosylation, the protein migrates to 80- 95KDa based on Bis-Tris PAGE result. |
Protein length : | It contains Leu22-Asp369. |
Endotoxin : | Less than 0. 01EU per ug by the LAL method. |
Purity : | > 95% as determined by SDS-PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | FGFR4 fibroblast growth factor receptor 4 [ Homo sapiens ] |
Official Symbol : | FGFR4 |
Synonyms : | CD334 antigen; CD334; EC 2. 7. 10; EC 2. 7. 10. 1; FGF R4; FGFR4; FGFR-4; fibroblast growth factor receptor 4; JTK2hydroxyaryl-protein kinase; MGC20292; protein-tyrosine kinase; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase |
Gene ID : | 2264 |
mRNA Refseq : | NM_002011 |
Protein Refseq : | NP_002002 |
MIM : | 134935 |
UniProt ID : | P22455 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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