Active Recombinant Human Fibronectin Protein, 1358aa-2301aa, C-His tagged

• Cat.No.: FN1-10H
• Product Overview: Recombinant Human FN1 Protein (1358aa-2301aa) with C-His tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 1358aa-2301aa
• Description: Fibronectin is utilized in T cell culture as a substrate to enhance adhesion, proliferation, and activation of T cells. By mimicking the extracellular matrix, fibronectin promotes T cell attachment and facilitates signaling pathways crucial for T cell function and survival. This application is vital for studying T cell biology, immunotherapy development, and understanding immune responses in various diseases.
• Form: Liquid
• Bio-activity: T-cell proliferation and activation activity
• AA Sequence: VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPAKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEILVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYGGGGSHHHHHHHHHH*
• Endotoxin: ≤ 0.25 EU/mg by the LAL method
• Purity: > 95% determined by SDS-PAGE (Reduced)
• Storage Buffer: 12.5 mM sodium citrate (pH 6.2) and 1.25% sucrose

Gene Information

• Gene Name: FN1 fibronectin 1 [ Homo sapiens (human) ]
• Official Symbol: FN1
• Synonyms: FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149
• Gene ID: 2335
• mRNA Refseq: NM_002026
• Protein Refseq: NP_002017
• MIM: 135600
• UniProt ID: P02751