Active Recombinant Human HSPA5 protein, His-tagged

• Cat.No.: HSPA5-1551H
• Product Overview: Recombinant full length (aa 1-654) human GRP78 BiP Protein with His tag.

Specification

• Description: The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 20 mM Tris-HCl, pH 7.5, 50 mM KCl, 1 mM DTT, 5 mM MgCl2.
• Bio-activity: GRP78 has ATPase activity at the time of manufacture of 2.3 μM phosphate liberated/hr/μg protein in a 200 μl reaction at 37 centigrade (pH7.5) in the presence of 20 μl of 1 mM ATP using a Malachite Green assay.
• Molecular Mass: 78 kDa
• Storage: Stable for 2 years at -70 centigrade from date of shipment. Please aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [ Homo sapiens ]
• Official Symbol: HSPA5
• Synonyms: HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); GRP78, heat shock 70kD protein 5 (glucose regulated protein, 78kD); 78 kDa glucose-regulated protein; BiP; immunoglobulin heavy chain-binding protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; BIP; MIF2; GRP78; FLJ26106
• Gene ID: 3309
• mRNA Refseq: NM_005347
• Protein Refseq: NP_005338
• MIM: 138120
• UniProt ID: P11021