Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse Hspa5 Protein, His-tagged

Cat.No. : Hspa5-238M
Product Overview : Recombinant Mouse Hspa5(20-655aa) fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : HSPA5, also known as 78 kDa glucose-regulated protein precursor, is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.
Source : E. coli
Species : Mouse
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 72.9 kDa (659aa) Confirmed by MALDI-TOF
Protein length : 20-655aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSEEEDKKE DVGTVVGIDL GTTYSCVGVF KNGRVEIIAN DQGNRITPSY VAFTPEGERL IGDAAKNQLT
SNPENTVFDA KRLIGRTWND PSVQQDIKFL PFKVVEKKTK PYIQVDIGGG QTKTFAPEEI SAMVLTKMKE TAEAYLGKKV THAVVTVPAY
FNDAQRQATK DAGTIAGLNV MRIINEPTAA AIAYGLDKRE GEKNILVFDL GGGTFDVSLL TIDNGVFEVV ATNGDTHLGG EDFDQRVMEH
FIKLYKKKTG KDVRKDNRAV QKLRREVEKA KRALSSQHQA RIEIESFFEG EDFSETLTRA KFEELNMDLF RSTMKPVQKV LEDSDLKKSD
IDEIVLVGGS TRIPKIQQLV KEFFNGKEPS RGINPDEAVA YGAAVQAGVL SGDQDTGDLV LLDVCPLTLG IETVGGVMTK LIPRNTVVPT
KKSQIFSTAS DNQPTVTIKV YEGERPLTKD NHLLGTFDLT GIPPAPRGVP QIEVTFEIDV NGILRVTAED KGTGNKNKIT ITNDQNRLTP
EEIERMVNDA EKFAEEDKKL KERIDTRNEL ESYAYSLKNQ IGDKEKLGGK LSSEDKETME KAVEEKIEWL ESHQDADIED FKAKKKELEE
IVQPIISKLY GSGGPPPTGE EDTSEKDEL
Purity : > 90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Absorbance at 280)
Gene Name : Hspa5 heat shock protein 5 [ Mus musculus ]
Official Symbol : Hspa5
Synonyms : HSPA5; heat shock protein 5; 78 kDa glucose-regulated protein; GRP-78; XAP-1 antigen; heat shock 70 kDa protein 5; glucose regulated protein, 78 kDa; immunoglobulin heavy chain-binding protein; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); Bip; Sez7; mBiP; Grp78; SEZ-7; Hsce70; AL022860; AU019543; D2Wsu17e; D2Wsu141e;
Gene ID : 14828
mRNA Refseq : NM_022310
Protein Refseq : NP_071705
UniProt ID : P20029

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there drugs targeting HSPA5 currently in development? 03/16/2021

Some studies explore small molecules and compounds that target HSPA5 as potential therapeutic agents, but clinical applications are still under investigation.

In what other medical conditions is HSPA5 relevant? 01/27/2021

HSPA5 is involved in various conditions, including cardiovascular diseases, diabetes, and neurodegenerative disorders.

Are there diagnostic applications of HSPA5 in cancer? 03/16/2018

Elevated levels of HSPA5 in certain cancers may serve as a diagnostic marker, providing information about the cellular stress response and potential malignancy.

Is there a relationship between HSPA5 and autoimmune disorders? 11/19/2017

HSPA5's involvement in the immune response suggests potential links to autoimmune disorders, but specific mechanisms are still being studied.

How does HSPA5 influence the immune response? 03/25/2016

HSPA5 is involved in antigen presentation, linking its role in protein folding to the modulation of immune responses.

Customer Reviews (3)

Write a review
Reviews
07/02/2022

    This level of support ensures that researchers have a seamless experience, enabling them to focus on their research goals without worrying about logistical or technical concerns.

    01/18/2020

      Its versatility in various biological applications, along with its compatibility with different techniques, strongly recommend it as a preferred reagent for researchers in the field.

      07/07/2019

        researchers highly appreciate HSPA5 protein for its excellent performance in ELISA assays and protein electron microscopy structure analysis.

        Ask a Question for All Hspa5 Products

        Required fields are marked with *

        My Review for All Hspa5 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends