Active Recombinant Human IFNA2A Protein (165 aa)
Cat.No. : | IFNA2-382I |
Product Overview : | Recombinant Interferon-Alpha 2a (IFN-Alpha 2a), Human produced in E. coli is a single non-glycosylated polypeptide chain containing 165 amino acids. A fully biologically active molecule, rhIFN-Alpha has a molecular mass of 19.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Interferon-Alpha 2a (IFN-Alpha 2a), Human produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections. IFN-alpha 2 has three acid stable forms (a,b,c) signaling through IFNAR2. IFN-alpha 2a shares 99.4%, 98.8% aa sequence identity with IFN-alpha 2b and 2c respectively. IFN-alpha contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. |
Source : | E. coli |
Species : | Human |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50 < 0.1 ng/mL, measured by a cytotoxicity assay using TF-1 Cells, corresponding to a specific activity of > 1.0 × 10^7 units/mg. |
Molecular Mass : | 19.2kDa, observed by reducing SDS-PAGE. |
Protein Length : | 165 |
AA Sequence : | CDLPQTHSLGSRRTLMLLAQMRKIS LFSCLKDRHDFGFPQEEFGNQFQKA ETIPVLHEMIQQIFNLFSTKDSSAA WDETLLDKFYTELYQQLNDLEACVI QGVGVTETPLMKEDSILAVRKYFQR ITLYLKEKKYSPCAWEVVRAEIMRS FSLSTNLQESLRSKE |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% by SDS-PAGE and HPLC analyses. |
Storage : | Lyophilized recombinant human Interferon-Alpha 2a (rhIFN-Alpha 2a) remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, rhIFN-Alpha 2a should be stable up to 2 weeks at 4 centigrade or up to 3 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O at 100 μg/mL. |
Gene Name : | IFNA2 interferon alpha 2 [ Homo sapiens (human) ] |
Official Symbol : | IFNA2 |
Synonyms : | IFNA2; interferon alpha 2; IFNA; IFNA2B; leIF A; IFN-alphaA; IFN-alpha-2; interferon alpha-2alpha-2a interferoninterferon alpha 2ainterferon alpha 2binterferon alpha A |
Gene ID : | 3440 |
mRNA Refseq : | NM_000605 |
Protein Refseq : | NP_000596 |
MIM : | 147562 |
UniProt ID : | P01563 |
Products Types
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IFNA2-2517H | Recombinant Human IFNA2 protein(61-180 aa), C-His-tagged | +Inquiry |
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IFNA2-114H | Active Recombinant Human IFN-alpha 2b Protein | +Inquiry |
◆ Lysates | ||
IFNA2-1634MCL | Recombinant Mouse IFNA2 cell lysate | +Inquiry |
IFNA2-954CCL | Recombinant Cynomolgus IFNA2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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