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Official Full Name IFNA2 interferon, alpha 2
Background Interferon alpha (IFN alpha) is a glycosylated protein which is produced by many cell types such as monocytes, macrophages, ?broblasts in response to virus infection, nucleic acid induction, glucocorticoid hormones. Some of the other biological effects, including antitumor and immunomodulatory activities IFN-alpha ’s most important function is the antiviral activity. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides. Some other biological processes involving IFN alpha are:induction of apoptosis, signal transduction, in?ammatory response. IFN alpha activates cytotoxic T-cells. IFN alpha binds to its receptors, which upon dimerisation, activate the JAK-STAT pathway.
Synonyms IFNA2; interferon, alpha 2; interferon alpha-2; alpha 2a interferon; IFN alphaA; IFNA; interferon alpha 2b; interferon alpha A; leIF A; IFN-alpha-2; alpha-2a interferon; INFA2; IFNA2B; IFN-alphaA; MGC125764; MGC125765
    • Species :
    • Cynomolgus Monkey
    • Feline
    • Human
    • Monkey
    • Mouse
    • Porcine
    • Rat
    • Rhesus Macaque
    • Source :
    • Barley Grain
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Monkey
    • Nicotiana Benthamiana
    • Nicotiana Sp.
    • P.pastoris
    • Pseudomonas Putida
    • S.cerevisiae
    • Yeast
    • Tag :
    • Fc
    • His
    • GST
    • HQ
    • HSA
    • Myc
    • DDK
    • N/A
    • N-Human Albumin
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IFNA2-009N Recombinant Human Interferon, Alpha 2, His-tagged Nicotiana Benthamiana His
    Human IFNA2-01H Recombinant Human IFNA2 protein Yeast N/A
    Human IFNA2-02H Recombinant Human Pegylated Interferon Alpha-2a E.coli N/A
    Human IFNA2-03H Recombinant Human IFNA2 protein E.coli N/A
    Human IFNA2-05H Recombinant Human Pegylated Interferon Alpha-2b E.coli N/A
    Human IFNA2-1188H Recombinant Human IFNA2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IFNA2-139H Recombinant Human Interferon, Alpha 2, HQ-tagged Barley Grain HQ
    Human IFNA2-1554H Recombinant human IFNA2, Active, His-tagged Nicotiana Benthamiana His
    Human IFNA2-1555H Recombinant Human IFNA2 Protein, His-tagged Nicotiana Sp. His
    Human IFNA2-169H Recombinant Human IFNA2 Protein, His-tagged E.coli His
    Human IFNA2-16H Recombinant Human IFNA2 protein Yeast N/A
    Human IFNA2-170H Recombinant Human IFNA2 Protein, His/GST-tagged E.coli His/GST
    Human IFNA2-17H Recombinant Human Interferon, Alpha 2, His-tagged Nicotiana Sp. His
    Human IFNA2-189H Recombinant Human IFNA2 Protein, HSA-tagged P.pastoris HSA
    Human IFNA2-222H Recombinant Human IFNA2, StrepII-tagged Human Cell Strep II
    Human IFNA2-24H Recombinant Human IFNA2 P.pastoris N/A
    Human IFNA2-29497TH Recombinant Human IFNA2 E.coli N/A
    Human IFNA2-29498TH Recombinant Human IFNA2 N/A
    Human IFNA2-532H Recombinant Human IFNA2 E.coli N/A
    Human IFNA2-59H Recombinant Human Interferon, Alpha 2 S.cerevisiae N/A
    Human IFNA2-8514H Recombinant Human IFNA2, N-Human Albumin-tagged Yeast N-Human Albumin
    Human IFNA2-91H Recombinant Human Interferon, Alpha 2 Pseudomonas Putida N/A
    Human IFNA2-P008H Recombinant Human IFNA2 therapeutic protein E.coli N/A
    Human INFA2-04H Recombinant Human HSA-Interferon Alpha-2b Yeast N/A
    Mouse Ifna2-15M Recombinant Mouse Ifna2 E.coli N/A
    Mouse IFNA2-1634MCL Recombinant Mouse IFNA2 cell lysate Human Cell N/A
    Mouse Ifna2-875M Recombinant Mouse Ifna2 Protein Yeast N/A
    Mouse Ifna2-88M Recombinant Mouse Interferon Alpha 2 E.coli N/A
    Mouse Ifna2-89M Recombinant Mouse Ifna2, Fc tagged Human Cell Fc
    Rat Ifna2-171R Recombinant Rat Ifna2 Protein, His-tagged E.coli His
    Cynomolgus Monkey IFNA2-72C Recombinant Cynomolgus IFNA2, His tagged Human Cell Fc
    Cynomolgus Monkey IFNA2-8830C Recombinant Cynomolgus IFNA2, Fc tagged Human Cell Fc/His
    Cynomolgus Monkey IFNA2-954CCL Recombinant Cynomolgus IFNA2 cell lysate Human Cell N/A
    Rhesus Macaque IFNA2-1192R Recombinant Rhesus IFNA2 Protein Yeast N/A
    Rhesus Macaque IFNA2-2204R Recombinant Rhesus monkey IFNA2 Protein, His-tagged Mammalian Cell His
    Monkey IFNA2-117M Recombinant Monkey Interferon, Alpha 2 Monkey N/A
    Feline IFNA2-548F Recombinant Feline IFNA2 E.coli N/A
    Porcine IFNA2-601P Recombinant Porcine IFNA2 Mammalian Cell N/A

    ifna2 involved in several pathways and played different roles in them. We selected most pathways ifna2 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ifna2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CCL19; TNFSF10; GDF5; CCL23; VEGFB; Ccl21a; Flt3l; BMP2; IL1RAP; M17
    Regulation of autophagy IFNA10; INS1; BECN1; IFNA3; IFNA1; ATG4A; INS; ULK3; ATG7; GABARAP
    PIK-Akt signaling pathway Fgf15; FGF3; KITLG; IFNA13; PRKAA1; IFNA5; PIK3CB; ITGB3; BCL2L1; IFNB1
    Toll-like receptor signaling pathway NFKBIA; IFNA2; IFNA1; IFNB; MAPK3; RIPK1L; MAP2K4B; CCL4; MAP2K7; STAT1
    RIG-I-like receptor signaling pathway NLRX1; IFNW1; PIN1; IL12A; SIKE1; NT5C3; IL8L2; NFKBIA; TBK1; IKBKG
    Cytosolic DNA-sensing pathway IFNA8; POLR2F; RIPK1; IKBKG; POLR2E; RIPK1L; Ifna15; NFKBIAB; ZBP1; POLR2L
    Jak-STAT signaling pathway IL2RB; CTF1; IFNA6; IL6R; PIAS4; PRLR; SOCS4; FHL1; IFNA3; STAT2
    Natural killer cell mediated cytotoxicity RAF1; RAET1L; SH2D1B; LCP2; PRF1; PIK3R5; MAP2K2; ICAM2; PPP3CC; Casp3
    Tuberculosis FCGR2B; Il23a; HLA-DQA2; LAMP1; LAMP2; FCGR3A; RAB5B; BID; MAPK3; ATP6V0D1
    Hepatitis C TRAF2; CLDN18; PPP2R2A; MAPK1; NFKBIA; CLDN23; IL-8; IFNA16; PIK3CA; IFNA21
    Hepatitis B TLR3; YWHAB; STAT2; Ifna15; NFKB1; IFNA10; MAP3K1; PTK2B; PIK3R1; BIRC5
    Measles TNFRSF10C; Cd209g; FAS; IL13; Il2; TLR2; IFNGR2; CD209C; STAT3; CD209B
    Influenza A IL33; RSAD2; BMA2; RAF1; CXCL8; MAP2K4; XPO1; MAVS; IFNAR1; CASP9
    Herpes simplex infection IFNGR2; IL15; CD74A; PPP1CB; CDC34A; TLR2-2; HLA-DRB1; BLB1; HLA-DOB; FAS
    ne thyroid disease TG; IFNA13; HLA-DQA2; HLA-DRB4; IFNA10; HLA-DOA; HLA-DPB1; IFNA6; HLA-DRB3; IFNA12

    ifna2 has several biochemical functions, for example, cytokine activity, protein binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ifna2 itself. We selected most functions ifna2 had, and list some proteins which have the same functions with ifna2. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IFNA7; GDF6; GPI; C1QTNF4; CCL19A.1; IL6; Cxcl15; Ccl27a; GDF11; IFNA1
    protein binding SLC4A1A; GRM1; SMAD3A; DNAJB11; HNRPDL; KRTAP8-1; EMP3; ACTL6A; MYOD1; KEAP1
    type I interferon receptor binding GM13287; Gm13290; RNF207B; GM13289; IFNA6; IFNPHI2; IFNA3; IFNE; IFNA21; IFNB

    ifna2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ifna2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ifna2.


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