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IFNA2

  • Official Full Name

    IFNA2 interferon, alpha 2

  • Overview

    Interferon alpha (IFN alpha) is a glycosylated protein which is produced by many cell types such as monocytes, macrophages, ?broblasts in response to virus infection, nucleic acid induction, glucocorticoid hormones. Some of the other biological effects, including antitumor and immunomodulatory activities IFN-alpha ’s most important function is the antiviral activity. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides. Some other biological processes involving IFN alpha are:induction of apoptosis, signal transduction, in?ammatory response. IFN alpha activates cytotoxic T-cells. IFN alpha binds to its receptors, which upon dimerisation, activate the JAK-STAT pathway.
  • Synonyms

    IFNA2; interferon, alpha 2; interferon alpha-2; alpha 2a interferon; IFN alphaA; IFNA; interferon alpha 2b; interferon alpha A; leIF A; IFN-alpha-2; alpha-2a interferon; INFA2; IFNA2B; IFN-alphaA; MGC125764; MGC125765;

  • Recombinant Proteins
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Therapeutic Proteins
  • Cell & Tissue Lysates
  • Cynomolgus Monkey
  • Feline
  • Human
  • Monkey
  • Mouse
  • Porcine
  • Rat
  • Rhesus
  • Rhesus Macaque
  • Barley Grain
  • CHO
  • E.coli
  • HEK293
  • HEK293F
  • Human Cell
  • Human cells
  • Mammalian Cell
  • Mammalian cells
  • Monkey
  • Nicotiana Benthamiana
  • Nicotiana Sp.
  • P.pastoris
  • Pseudomonas Putida
  • S.cerevisiae
  • Yeast
  • C
  • His
  • Fc
  • Fc|His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • HQ
  • HSA
  • mFc
  • Myc|DDK
  • N/A
  • N
  • hFc
  • Human Albumin
  • MBP
  • Strep II
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IFNA2-8514H Active Recombinant Human IFNA2, N-Human Albumin-tagged Yeast N-Human Albumin
Human IFNA2-189H Active Recombinant Human IFNA2 Protein, HSA-tagged P.pastoris HSA Cys24-Glu188
Human IFNA2-106I Active Recombinant Human IFNA2B Protein (165 aa) S.cerevisiae 165
Human IFNA2-20HG Active GMP Recombinant Human IFNA2 Protein HEK293 N/A
Human IFNA2-628H Active Recombinant Human IFNA2 Protein E.coli Tag Free
Human IFNA2-1261H Acitve Recombinant Human IFNA2 protein(Cys24-Glu188) Yeast N/A Cys24-Glu188
Human IFNA2-06HG GMP Recombinant Human Interferon Alpha-2b, Cys24-Glu188 CHO N/A Cys24-Glu188
Human IFNA2-16H Recombinant Human IFNA2 protein Yeast N/A 165
Human IFNA2-29497TH Recombinant Human IFNA2 E.coli N/A
Human IFNA2-169H Recombinant Human IFNA2 Protein, His-tagged E.coli His Cys24~Glu188
Human IFNA2-170H Recombinant Human IFNA2 Protein, His/GST-tagged E.coli His/GST Cys24~Glu188
Human IFNA2-1554H Recombinant human IFNA2, Active, His-tagged Nicotiana Benthamiana His
Human IFNA2-29498TH Recombinant Human IFNA2 N/A
Human IFNA2-24H Recombinant Human IFNA2 P.pastoris N/A
Human INFA2-04H Recombinant Human HSA-Interferon Alpha-2b Yeast N/A
Human IFNA2-139H Recombinant Human Interferon, Alpha 2, HQ-tagged Barley Grain HQ
Human IFNA2-91H Recombinant Human Interferon, Alpha 2 Pseudomonas Putida N/A
Human IFNA2-01H Recombinant Human IFNA2 protein Yeast N/A 165
Human IFNA2-222H Recombinant Human IFNA2, StrepII-tagged Human Cell Strep II 24-188, 165 a.a.
Human IFNA2-02H Recombinant Human Pegylated Interferon Alpha-2a E.coli N/A
Human IFNA2-59H Recombinant Human Interferon, Alpha 2 S.cerevisiae N/A
Human IFNA2-17H Recombinant Human Interferon, Alpha 2, His-tagged Nicotiana Sp. His
Human IFNA2-009N Recombinant Human Interferon, Alpha 2, His-tagged Nicotiana Benthamiana His
Human IFNA2-03H Recombinant Human IFNA2 protein E.coli N/A 166
Human IFNA2-05H Recombinant Human Pegylated Interferon Alpha-2b E.coli N/A
Human IFNA2-1148H-B Recombinant Human IFNA2 Protein Pre-coupled Magnetic Beads HEK293
Human IFNA2-1555H Active Recombinant Human IFNA2 Protein, His-tagged Nicotiana Sp. His
Human IFNA2-P008H Recombinant Human IFNA2 therapeutic protein E.coli N/A 165aa
Human IFNA2-2518H Recombinant Human IFNA2 protein(24-188 aa), C-His-tagged E.coli C-His 24-188 aa
Human IFNA2-0584H Recombinant Human IFNA2 Protein (Cys24-Glu188), Tag Free Yeast Tag Free Cys24-Glu188
Human IFNA2-4181H Recombinant Human IFNA2 protein, GST-tagged E.coli GST 24-188aa
Human IFNA2-075H Active Recombinant Human IFNA2 Protein E.coli
Human IFNA2-2519H Recombinant Human IFNA2 protein(24-188 aa), C-His-tagged HEK293 C-His 24-188 aa
Human IFNA2-2881H Recombinant Human Full length IFNA2 protein(1-188 aa), C-His-tagged HEK293 C-His 1-188 aa
Human IFNA2-2517H Recombinant Human IFNA2 protein(61-180 aa), C-His-tagged E.coli C-His 61-180 aa
Human IFNA2-381I Active Recombinant Human IFNA2B Protein (165 aa) E.coli 165
Human IFNA2-2520H Recombinant Human IFNA2 protein(24-188 aa), N-MBP & C-His-tagged HEK293 N-MBP & C-His 24-188 aa
Human IFNA2-5696H Recombinant Human IFNA2 protein, His-tagged Yeast His 24-188aa
Human IFNA2-113H Active Recombinant Human IFN-alpha 2a Protein E.coli
Human IFNA2-0256H Active Recombinant Human IFNA2 protein, Fc-tagged HEK293 Fc Cys24-Glu188
Human IFNA2-1188H Recombinant Human IFNA2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IFNA2-1913HFL Recombinant Full Length Human IFNA2 Protein, C-Flag-tagged Mammalian cells Flag
Human IFNA2-382I Active Recombinant Human IFNA2A Protein (165 aa) E.coli 165
Human IFNA2-114H Active Recombinant Human IFN-alpha 2b Protein E.coli
Human IFNA2-2270H Recombinant Human IFNA2 Protein, His-tagged E.coli N-His Cys24-Glu188
Human IFNA2-20H Active Recombinant Human IFNA2 Protein, Animal Free Human cells
Human IFNA2-1148H Recombinant Human IFNA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IFNA2-2499H Recombinant Human IFNA2 Protein (Cys24-Glu188), His tagged E.coli His Cys24-Glu188
Human IFNA2-103H Recombinant Human IFNA2 Protein E.coli
Human IFNa2-1265H Recombinant Human IFNa2 protein, His-tagged HEK293 His Cys24~Glu188
Human IFNA2-10H Active Recombinant Human IFNA2 Protein (24-188aa) E.coli 24-188aa
Mouse Ifna2-15M Active Recombinant Mouse Ifna2 E.coli N/A
Mouse Ifna2-875M Active Recombinant Mouse Ifna2 protein Yeast N/A Cys24-Glu190
Mouse Ifna2-88M Active Recombinant Mouse Interferon Alpha 2 E.coli N/A
Mouse Ifna2-89M Active Recombinant Mouse Ifna2 protein(Cys24-Glu190), hFc-tagged HEK293 N-hFc Cys24-Glu190
Mouse IFNA2-1634MCL Recombinant Mouse IFNA2 cell lysate Human Cell N/A
Mouse Ifna2-977M Recombinant Mouse Ifna2 Protein, His-tagged HEK293F N-His Cys21-Lys186
Mouse IFNA2-80M Recombinant Mouse IFNA2 Protein E.coli
Rat Ifna2-171R Recombinant Rat Ifna2 Protein, His-tagged E.coli His Cys24~Ser192
Monkey IFNA2-117M Active Recombinant Monkey Interferon, Alpha 2 Monkey N/A
Cynomolgus Monkey IFNA2-72C Recombinant Cynomolgus IFNA2, His tagged Human Cell Fc
Cynomolgus Monkey IFNA2-8830C Recombinant Cynomolgus IFNA2, Fc tagged Human Cell Fc/His
Cynomolgus Monkey IFNA2-954CCL Recombinant Cynomolgus IFNA2 cell lysate Human Cell N/A
Feline IFNA2-548F Recombinant Feline IFNA2 E.coli N/A
Porcine IFNA2-601P Active Recombinant Porcine IFNA2 Mammalian Cell N/A
Porcine IFNA2-1P Recombinant Porcine IFNA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Porcine IFNA2-1P-B Recombinant Porcine IFNA2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus IFNA2-1192R Active Recombinant Rhesus IFNA2 protein Yeast N/A Cys24-Glu188
Rhesus IFNA2-231R Active Recombinant Rhesus IFNA2 protein, His-tagged HEK293 His Met1-Glu188
Rhesus IFNA2-1112R Active Recombinant Rhesus IFNA2 protein, mFc-tagged HEK293 mFc Met1-Glu188
Rhesus Macaque IFNA2-2204R Recombinant Rhesus monkey IFNA2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque IFNA2-2026R Recombinant Rhesus Macaque IFNA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IFNA2-2026R-B Recombinant Rhesus Macaque IFNA2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IFNA2 involved in several pathways and played different roles in them. We selected most pathways IFNA2 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL9;OSM;CXCL12A;IL18;TNFRSF21;LEPA;TP-1;IL23;IL1R1
Regulation of autophagyIFNA17;IFNA16;IFNA3;ULK3;IFNA1;ULK2;IFNA2;PRKAA2;INS
PIK-Akt signaling pathwayLAMB1;PDGFD;FGF13;RBL2;NGF;IL2RG;ITGB5;HSP90B1;IFNA4
Toll-like receptor signaling pathwayIFNPHI1;IFNA6;IRF3;NFKB1;MAPK1;PIK3R1;TLR3;CCL5;PIK3R3A
RIG-I-like receptor signaling pathwayRNF125;MAPK8B;IL12B;IFNA1;SIKE1;CASP8;DDX3X;AZI2;IFNA7
Cytosolic DNA-sensing pathwayPOLR3F;OSTN;NFKB1;POLR3B;POLR3GLB;Ifna11;CCL4L2;POLR3C;POLR2L
Jak-STAT signaling pathwayIL29;SOCS1A;PTPN6;IL12RB2;PIK3CD;Gh;PRP2;RAF1A;CCND2A
Natural killer cell mediated cytotoxicityKIR2DS4;KLRA8;ITGAL;KIR2DL3;PPP3R2;TYROBP;IFNAR2;KRAS;KIR2DL4
TuberculosisFCGR2A;RHOA;ITGAM;VDR;CLEC4E;CALM4;MAPK9;RIPK2;FCGR2B
Hepatitis CCLDN10;IFIT1;OAS1B;IFN-a;OAS2;MAPK1;KRAS;IKBKB;IFNA5
Hepatitis BIfna11;BAD;YWHAZ;PIK3R3;CASP12;TGFB2;CASP10;PTK2B;FADD
MeaslesIL6;IL13;CD3G;PIK3CA;TBK1;TNFAIP3;IL2RG;CCND1;EIF3H
Influenza ANLRX1;Ccl12;PLG;OAS1A;IFN-a;IFNB1;ACTG1;OAS1B;PABPN1
Herpes simplex infectionMAPK9;CYCSB;OAS2;HLA-DPA1;EIF2AK3;MED8;HCFC2;HNRNPK;TNFRSF1A
AutoiIfna11;GZMB;H2-AB1;TG;TPO;IFNA2;HLA-DRB5;IFNA5;IL5
ne thyroid diseaseIFNA17;Ifna11;CD28;Ifna15;IFNA2;HLA-DMA;HLA-C;CD40;PRF1

IFNA2 has several biochemical functions, for example, cytokine activity, protein binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA2 itself. We selected most functions IFNA2 had, and list some proteins which have the same functions with IFNA2. You can find most of the proteins on our site.

Function Related Protein
cytokine activityGm13290;GDF15;IL9;IL10;AREG;IFNG1-2;FGF2;TNFSF4;BMP7
protein bindingSRSF1;ANKRD32;KCNE2;BLK;RSPH1;C7orf53;SOCS7;SIGLEC6;TTC6
type I interferon receptor bindingIFNA16;OSTN;IFNA6;GM13287;IFNA1;IFNE;IFNK;IFNA8;IFNB1

IFNA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA2.

IFNAR2

Gene Family

Cytokines

Research Area

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