Active Recombinant Human IFNGR1 Protein, His-tagged

• Cat.No.: IFNGR1-71H
• Product Overview: IFNγR1 protein dimer contains IFNγR1 2 extracellular domains with a homodimer motif and a His tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293T
• Tag: His
• Protein Length: 18-245 aa
• Description: Interferon gamma receptor 1 (IFNγR1), also known as CD119, IMD27A and IMD27B, is a subunit of interferon gamma receptor (IFNγR). IFNγR belongs to the type II cytokine receptor family. IFNγR1 is a type I integral membrane glycoprotein containing extracellular, transmembrane and intracellular domains. The extracellular domain has two immunoglobulin-like (Ig-like) C2-type domains. The interferon gamma (IFNγ) dimer interacts with two IFNγR1 molecules to activate the cascade signaling pathway.
• Molecular Mass: 98 kDa
• Homodimer/Heterodimer: Homodimer
• Purity: >90% dimer form as determined by SDS PAGE under non-reducing conditions.
• Application: Verified Applications: ELISA for IFNγR1-specific antibody and IFNγ cytokine ligand protein binding assays. Suggested Applications: SPR & BLI for IFNγR1-specific antibody and IFNγ cytokine ligand protein binding assays. Animal immunization, RUO.
• Storage: At -80 centigrade
• Storage Buffer: 0.22μm filtered PBS, pH 7.4
• Shipping: Frozen Dry Ice

Gene Information

• Gene Name 2: IFNGR1 interferon gamma receptor 1 [Homo sapiens (human)]
• Official Symbol 2: IFNGR1
• Synonyms 2: IFNGR1; interferon gamma receptor 1; IFNGR; CD119; CDw119; AVP, type 2; IFN-gamma-R1; CD119 antigen; IFN-gamma receptor 1; antiviral protein, type 2; immune interferon receptor 1; interferon-gamma receptor alpha chain; FLJ45734
• Gene ID 2: 3459
• mRNA Refseq 2: NM_000416
• Protein Refseq 2: NP_000407
• MIM 2: 107470
• UniProt ID 2: P15260