Active Recombinant Mouse Ifngr1 Homodimer Protein, His tagged

• Cat.No.: Ifngr1-43M
• Product Overview: IFNγR1 protein dimer contains a IFNγR1 extracellular domain (UniProt# P15261) fused with a proprietary cis-dimer motif followed by a His tag at the C-terminus was expressed in HEK293T.

Specification

• Species: Mouse
• Source: HEK293T
• Tag: His
• Protein Length: 26-254 aa
• Description: Mouse interferon gamma receptor 1 (IFNγR1), also known as cluster of differentiation 119 (CD119), IMD27A and IMD27B, is a subunit of interferon gamma receptor (IFNγR). IFNγR belongs to the type II cytokine receptor family. IFNγR1 is a Type I integral membrane glycoprotein containing extracellular, transmembrane and intracellular domains. IFNγR consists of two subunits: IFNγR1 (ligand-binding) and IFNγR2 (signal transduction). The extracellular domain has two immunoglobulin-like (Ig-like) C2-type domains. The interferon gamma (IFNγ) protein interacts with two IFNγR1 molecules to activate the cascade signaling pathway. IFNγR is a crucial component of the JAK-STAT signaling pathway that mediates the biological effects of IFN-γ in mice.
• Molecular Mass: 68 kDa
• Purity: Greater than 90% dimer form as determined by SDS-PAGE under non-reducing condition
• Application: Verified Applications: ELISA for IFNγR1-specific antibody and interferon γ (IFNγ) ligand protein binding assays. SPR for IFNγR1-specific antibody and IFNγ ligand protein binding assays. Suggested Applications: BLI for IFNγR1-specific antibody and IFNγ protein dimer binding assays. Animal immunization, RUO.
• Storage: Store at -80 centigrade.
• Storage Buffer: 0.22μm filtered PBS, pH 7.4
• Shipping: Frozen Dry Ice

Gene Information

• Gene Name: Ifngr1 interferon gamma receptor 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ifngr1
• Synonyms: Ifngr1; interferon gamma receptor 1; Ifgr; CD119; Ifngr; Nktar; IFN-gammaR; interferon gamma receptor 1; IFN-gamma receptor 1; IFN-gamma-R-alpha; IFN-gamma-R1; INF-g receptor; interferon gamma receptor alpha-chain
• Gene ID: 15979
• mRNA Refseq: NM_010511
• Protein Refseq: NP_034641
• UniProt ID: P15261