Active Recombinant Human IFNL3, His-tagged

• Cat.No.: IFNL3-405H
• Product Overview: Recombinant Human IFNL3 (Accession # AAN28264) Arg30-Val200, fused with the variant of Lys74Arg and a C-terminal 6-His tag, was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Species: Human
• Source: CHO
• Tag: His
• Protein Length: 30-200 a.a.
• Predicted N Terminal: Arg30
• Form: Lyophilized from a 0.2 µm filtered solution in PBS, NaCl and EDTA with BSA as a carrier protein.
• Bio-activity: Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Sheppard, P. et al. (2003) Nat. Immunol. 4:63.The ED50 for this effect is typically 1 - 5 ng/mL.
• Molecular Mass: Recombinant Human IFNL3, His-tagged has a calculated MW of 20.1 kDa. In SDS-PAGE migrates as 22 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: IFNL3 interferon, lambda 3 [ Homo sapiens (human) ]
• Official Symbol: IFNL3
• Synonyms: IFNL3; interferon, lambda 3; IL28B; IL28C; IL-28B; interferon lambda-3; IFN-lambda-3; IFN-lambda-4; IL-28C; cytokine Zcyto22; interferon lambda-4; interferon, lambda 4; interleukin 28B (interferon, lambda 3); interleukin 28C; interleukin-28B; interleukin-28C
• Gene ID: 282617
• mRNA Refseq: NM_172139
• Protein Refseq: NP_742151
• MIM: 607402
• UniProt ID: Q8IZI9
• Chromosome Location: 19q13.13