Active Recombinant Human IGF1 protein

• Cat.No.: IGF1-09H
• Product Overview: Recombinant Human IGF1 was expressed in Rice Grain.

Specification

• Species: Human
• Source: Rice Grain
• Tag: Non
• Description: Human insulin-like growth factor-1, also known as IGF-1, has a molecular weight of 7.6 kD. It is hormone similar in molecular structure to insulin. It primarily functions through binding to its specific receptor, the insulin-like growth factor 1 receptpor(IGF1R), to initiates intracellular signaling. IGF-1 is one of the most potent narural activators of the AKT signaling pathway, which stimulates cell growth and prolifration, and inhibits cell apoptosis. Thus, IGF-1 is widely deemed as a powerful substitute of insulin. The product is expressed as fusion protein with HSA, which increase its solubility and lifetime. The product presents a molecular weight about 74.5 kD, and has a much higher stability compared to IGF-1.
• Form: It is lyophilized with phosphate.
• Bio-activity: >1x10^6 Units/mg.
• Molecular Mass: 74.5 kDa
• Endotoxin: < 5 EU/μg
• Purity: >95%
• Applications: 1. Mammalian cell culture;2. Cosmetic and beauty care;3. Healthcare products
• Storage: Stored at - 20 centigrade for at least 12 months. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended to reconstitute the lyophilized the product in strile water. Use as soon as possible after opening.
• Shipping: Ice pack

Gene Information

• Gene Name: IGF1 insulin-like growth factor 1 (somatomedin C) [ Homo sapiens ]
• Official Symbol: IGF1
• Synonyms: IGF1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor 1; IGF1A; MGF; IGF-IA; IGF-IB; somatomedin-C; mechano growth factor; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; IGFI; IGF-I
• Gene ID: 3479
• mRNA Refseq: NM_000618
• Protein Refseq: NP_000609
• MIM: 147440
• UniProt ID: P05019
• Chromosome Location: 12q23.2
• Pathway: Adipogenesis, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem
• Function: growth factor activity; hormone activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; integrin binding; protein binding