Active Recombinant Human IL17F Protein (133 aa)
| Cat.No. : | IL17F-099I |
| Product Overview : | Recombinant Human IL17F Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | Human IL-17F is synthesized as a 153 aa precursor with a 20 aa signal sequence and a 133 aa mature region. Like IL-17A, IL-17F contains one potential site for N-linked glycosylation. IL-17A and IL-17F share 50% aa sequence identity. IL17-F homodimer is produced by an activated subset of CD4+ T cells, termed Th17. IL17-F has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. |
| Source : | E. coli |
| Species : | Human |
| Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Bio-activity : | Measured by its ability to induce IL-6 production by NHDF cells, it’s fully biologically active when compared to standard. |
| Molecular Mass : | A disulfide-linked homodimer of 30.1kDa, consisting of two 133 amino acid polypeptide chains. |
| Protein Length : | 133 |
| AA Sequence : | MRKIPKVGHTFFQKPESCPPVPGGS MKLDIGIINENQRVSMSRNIESRST SPWNYTVTWDPNRYPSEVVQAQCRN LGCINAQGKEDISMNSVPIQQETLV VRRKHQGCSVSFQLEKVLVTVGCTC VTPVIHHVQ |
| Endotoxin : | Less than 1 EU/μg of rHuIL-17F as determined by LAL method. |
| Purity : | >95% by SDS-PAGE and HPLC analyses. |
| Storage : | This lyophilized preparation is stable for several weeks at 2-8 centigrade, but should be kept at -20 centigrade for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 centigrade. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 to -70 centigrade. Avoid repeated freeze/thaw cycles. |
| Storage Buffer : | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 4 mM HCl to a concentration of 0.1mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20C. Further dilutions should be made in appropriate buffered solutions. |
| Gene Name : | IL17F interleukin 17F [ Homo sapiens ] |
| Official Symbol : | IL17F |
| Synonyms : | IL17F; interleukin 17F; interleukin-17F; IL 17F; ML 1; ML1; IL-24; cytokine ML-1; mutant IL-17F; interleukin-24; ML-1; CANDF6; IL-17F; |
| Gene ID : | 112744 |
| mRNA Refseq : | NM_052872 |
| Protein Refseq : | NP_443104 |
| MIM : | 606496 |
| UniProt ID : | Q96PD4 |
Products Types
| ◆ Recombinant Protein | ||
| Il17f-142M | Recombinant Mouse Il17f Protein | +Inquiry |
| IL17F-145R | Active Recombinant Rat IL17F Protein | +Inquiry |
| IL17F-151H | Recombinant Active Human IL17F Protein, His-tagged(C-ter) | +Inquiry |
| IL17F-28H | Active Recombinant Human IL17F Protein, Animal Free | +Inquiry |
| IL17F-1009H | Recombinant Human IL17F Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| IL17F-2045HCL | Recombinant Human IL17F cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (10)
Ask a questionTumor xenografts, immune cell infiltration analysis, and therapeutic antibody testing assess IL17F's role in cancer.
Neutrophil chemotaxis assays, in vivo neutrophil tracking, and immune cell activation analysis explore IL17F's impact on neutrophil functions.
Genetic knockout models, functional assays, and gene expression analyses distinguish IL17F's unique roles.
Microbiota composition analysis, germ-free models, and immune cell profiling investigate IL17F-microbiota interactions.
Animal disease models, patient samples, and immunological assays elucidate IL17F's contribution to autoimmune diseases.
Co-immunoprecipitation, fluorescence resonance energy transfer (FRET), and pathway-specific assays elucidate IL17F's heterodimerization and signaling.
Comparative cytokine profiling, inflammatory assays, and pathway analysis dissect IL17F's interplay with other immune mediators.
Allergen challenges, inflammatory disease models, and gene expression profiling probe IL17F's involvement in chronic conditions.
Epithelial barrier permeability assays, tissue section analysis, and cell culture models study IL17F's effects on barrier integrity.
Wound healing assays, tissue regeneration models, and histological analyses examine IL17F's effects on tissue repair.
Customer Reviews (3)
Write a reviewHigh specificity. -
Good for receptor studies. -
Potent in anti-bacterial assays. -
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