Active Recombinant Human IL18 protein
Cat.No. : | IL18-336H |
Product Overview : | Recombinant Human IL18 was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-gamma)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. |
Source : | E. coli |
Species : | Human |
Form : | Liquid. In Phosphate buffer saline (pH 7.4) |
Bio-activity : | Measured by its ability to induce IFN-gamma secretion using KG-1 human myeloid leukemia cells in the presence of TNF-alpha (20 ng/ml). The ED50 for this effect is < 0.85 ug/ml. |
Molecular Mass : | 18.3kDa (158aa), confirmed by MALDI-TOF. |
AA Sequence : | MYFGKLESKL SVIRNLNDQV LFIDQGNRPL FEDMTDSDCR DNAPRTIFII SMYKDSQPRG MAVTISVKCE KISTLSCENK IISFKEMNPPDNIKDTKSDI IFFQRSVPGH DNKMQFESSS YEGYFLACEK ERDLFKLILK KEDELGDRSI MFTVQNED |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | > 95% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | IL18 interleukin 18 (interferon-gamma-inducing factor) [ Homo sapiens ] |
Official Symbol : | IL18 |
Synonyms : | IL18; interleukin 18 (interferon-gamma-inducing factor); interleukin-18; IGIF; IL 1g; IL 18; IL1F4; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; IL-18; IL-1g; MGC12320; |
Gene ID : | 3606 |
mRNA Refseq : | NM_001562 |
Protein Refseq : | NP_001553 |
MIM : | 600953 |
UniProt ID : | Q14116 |
Chromosome Location : | 11q22.2-q22.3 |
Pathway : | African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cellular roles of Anthrax toxin, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; |
Function : | cytokine activity; cytokine activity; |
Products Types
◆ Recombinant Protein | ||
IL18-1012H | Recombinant Human IL18 Protein, His-tagged | +Inquiry |
IL18-2297H | Recombinant Human IL18 Protein, His-tagged | +Inquiry |
IL18-1169H | Recombinant Human IL18 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL18-154H | Recombinant Active Human IL18 Protein, His-tagged(C-ter) | +Inquiry |
IL18-3681H | Recombinant Human IL18 protein(Met1-Asp193), GST-tagged | +Inquiry |
◆ Lysates | ||
IL18-344HCL | Recombinant Human IL18 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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