Active Recombinant Human IL22RA1, HIgG1 Fc-tagged
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Cat.No. : | IL22RA1-791H Optional Service: Optional requirements on this protein |
Product Overview : | The extracellular domain of human IL-22RA1 (AAH29273.1)(Pro18-Thr228) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell. |
Description : | The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be areceptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein andinterleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10(IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in thechromosomal region 1p36. |
Source : | CHO cell |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells. |
Molecular Mass : | 50KDa (monomer) |
AA Sequence : | Pro18-Thr228 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | IL22RA1 interleukin 22 receptor, alpha 1 [ Homo sapiens ] |
Official Symbol : | IL22RA1 |
Synonyms : | IL22RA1; interleukin 22 receptor, alpha 1; IL22R, interleukin 22 receptor; interleukin-22 receptor subunit alpha-1; CRF2 9; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9; IL22R; CRF2-9; IL22R1; |
Gene ID : | 58985 |
mRNA Refseq : | NM_021258 |
Protein Refseq : | NP_067081 |
MIM : | 605457 |
UniProt ID : | Q8N6P7 |
Chromosome Location : | 1p36.11 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
Function : | interferon receptor activity; receptor activity; |
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◆ Lysates
IL22RA1-768CCL | Recombinant Canine IL22RA1 cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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