Active Recombinant Human IL3RA protein, His-tagged
|Product Overview :||Recombinant Human IL3RA protein(Thr 19 - Arg 305), fused with His tag, was expressed in HEK293.|
- Gene Information
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|Form :||Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.|
|Bio-activity :||Human IL-3 R alpha, His Tag captured on CM5 Chip via anti-His antibody can bind Human IL-3, Tag Free with an affinity constant of 0.253 μM as determined in SPR assay (Biacore T200).|
|Molecular Mass :||This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 35.0 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Endotoxin :||Less than 1.0 EU per μg by the LAL method.|
|Purity :||>95% as determined by SDS-PAGE.>90% as determined by SEC-MALS.|
|Storage :||For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.|
|Gene Name :||IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ]|
|Official Symbol :||IL3RA|
|Synonyms :||IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; MGC34174;|
|Gene ID :||3563|
|mRNA Refseq :||NM_002183|
|Protein Refseq :||NP_002174|
|UniProt ID :||P26951|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
The feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.
Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.
Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.
Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.
The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.
Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.
Customer Reviews (3)Write a review
In special environment, good stability. -
Good crystallization property and good effect. -
Has the expected biological activity, such as enzyme activity and receptor binding activity, and so on. -
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