Active Recombinant Human IL5 Protein, His-Tagged
Cat.No. : | IL5-01H |
Product Overview : | Recombinant Human IL5 Protein, His-Tagged was expressed in Baculovirus cell line |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
Source : | Baculovirus |
Species : | Human |
Tag : | His |
Form : | Liquid |
Bio-activity : | Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤1.5ng/ml. |
Molecular Mass : | 14.2 kDa |
Protein length : | 124aa |
Endotoxin : | < 1 EU per 1ug of protein (determined by LAL method) |
Purity : | > 90% by SDS-PAGE |
Applications : | SDS-PAGE, Bioactivity |
Storage : | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by absorbance at 280nm) |
Storage Buffer : | Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | IL5 interleukin 5 [ Homo sapiens (human) ] |
Official Symbol : | IL5 |
Synonyms : | Interleukin-5, IL-5, EDF, TRF |
Gene ID : | 3567 |
mRNA Refseq : | NM_000879.3 |
Protein Refseq : | NP_000870.1 |
MIM : | 147850 |
UniProt ID : | P05113 |
Products Types
◆ Lysates | ||
IL5-456CCL | Recombinant Canine IL5 cell lysate | +Inquiry |
IL5-496MCL | Recombinant Mouse IL5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionInhibit the creatinine kinase level in the blood of patients with tuberous sclerosis, reduce the inflammatory response, and improve the quality of life of patients.
IL5 can reduce the number of eosinophils in the nasal mucosa of patients with allergic rhinitis, reducing the symptoms of allergic reactions, such as sneezing, runny nose and nasal congestion.
Stimulate the proliferation and differentiation of white blood cells, promote the function of the immune system, and is used to treat diseases such as asthma, allergic rhinitis, nodular sclerosis and some malignant tumors.
Cause mild side effects such as headache, nausea, vomiting, and serious side effects such as allergic reactions if the dose is too large or allergic.
IL5 cannot be administered orally, only by injection or intravenous drip.
IL5 can reduce the number of eosinophils in the lungs of asthma patients, reduce the frequency and severity of asthma attacks, and improve the quality of life of patients.
Customer Reviews (3)
Write a reviewHigh efficacy and safety in clinical treatment.
There are no structural or functional defects.
The stability and activity are maintained well during long-term storage.
Ask a Question for All IL5 Products
Required fields are marked with *
My Review for All IL5 Products
Required fields are marked with *
Inquiry Basket