Active Recombinant Human IMPDH1 Protein, His-Tagged
Cat.No. : | IMPDH1-01H |
Product Overview : | Recombinant Human IMPDH1 Protein, His-Tagged was expressed in sf21 cell |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. |
Source : | Sf21 insect cells |
Species : | Human |
Tag : | His |
Bio-activity : | Measured by its ability to convert the substrate inosine-5'-phosphate (IMP) to xanthosine-5'-phosphate (XMP). The specific activity is >100 pmol/min/μg, as measured under the described conditions. |
Molecular Mass : | 61 kDa |
N-terminal Sequence Analysis : | Met |
Endotoxin : | <1.0 EU per 1 μg of the protein by the LAL method. |
Purity : | >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening. |
Storage Buffer : | Supplied as a 0.2 μm filtered solution in Tris, NaCl, EDTA, Glycerol and TCEP. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
Gene Name : | IMPDH1 inosine monophosphate dehydrogenase 1 [ Homo sapiens (human) ] |
Official Symbol : | IMPDH1 |
Synonyms : | DKFZp781N0678, EC 1.1.1.205, IMP (inosine 5'-monophosphate) dehydrogenase 1, IMP (inosine monophosphate) dehydrogenase 1, IMP Dehydrogenase 1, IMPD, IMPD 1, IMPD1, IMPDH 1, IMPDH-I, IMPDH1, LCA11, LCA11RP10, RP10, inosine-5'-monophosphate dehydrogenase 1, retinitis pigmentosa 10 (autosomal dominant), sWSS2608 |
Gene ID : | 3614 |
mRNA Refseq : | NM_000883.4 |
Protein Refseq : | NP_899066 |
MIM : | 146690 |
UniProt ID : | P20839 |
Products Types
◆ Recombinant Protein | ||
IMPDH1-4534M | Recombinant Mouse IMPDH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Impdh1-3531M | Recombinant Mouse Impdh1 Protein, Myc/DDK-tagged | +Inquiry |
IMPDH1-5140H | Recombinant Human IMPDH1 Protein, GST-tagged | +Inquiry |
IMPDH1-8198M | Recombinant Mouse IMPDH1 Protein | +Inquiry |
IMPDH1-28268TH | Recombinant Human IMPDH1, His-tagged | +Inquiry |
◆ Lysates | ||
IMPDH1-5212HCL | Recombinant Human IMPDH1 293 Cell Lysate | +Inquiry |
IMPDH1-5211HCL | Recombinant Human IMPDH1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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