Active Recombinant Human ITGA4&ITGB1 protein, His-tagged
Cat.No. : | ITGA4&ITGB1-1571H |
Product Overview : | Recombinant Human ITGA4&ITGB1 protein(Tyr34-Thr977(ITGA4)&Gln21-Asp728(ITGB1)), fused with His tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
- Download
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5. |
Bio-activity : | Immobilized Natalizumab at 1 μg/mL (100 μL/well) can bind Human ITGA4&ITGB1 Heterodimer Protein, His Tag&Tag Free with a linear range of 1-16 ng/mL. |
Molecular Mass : | Human ITGA4&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA4 and ITGB1, has a calculated MW of 111.4 kDa (ITGA4) and 83.7 kDa (ITGB1). Subunit ITGA4 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The ITGA4 subunit is composed of a heavy chain (Tyr 34 - Arg 591, calculated MW 61.1 kDa) and a light chain (Ser 592 - Thr 977, calculated MW 50.1 kDa). Consequently ITGA4 migrates as 60-70 kDa, 80-85 kDa and 135-150 kDa, and ITGB1 as 100-133 kDa respectively under reducing (R) condition due to cleavage and glycosylation. |
Proteinlength : | Tyr34-Thr977(ITGA4)&Gln21-Asp728(ITGB1) |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) [ Homo sapiens ] |
Official Symbol : | ITGA4 |
Synonyms : | ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); CD49D; integrin alpha-4; CD49d; 269C wild type; integrin alpha 4; integrin alpha-IV; VLA-4 subunit alpha; integrin alpha-4 subunit; CD49 antigen-like family member D; antigen CD49D, alpha-4 subunit of VLA-4 receptor; very late activation protein 4 receptor, alpha 4 subunit; IA4; MGC90518; |
Gene ID : | 3676 |
mRNA Refseq : | NM_000885 |
Protein Refseq : | NP_000876 |
MIM : | 192975 |
UniProt ID : | P13612 |
Products Types
◆ Recombinant Protein | ||
ITGA4-2321H | Recombinant Human ITGA4 protein(376-558aa), His-GST-tagged | +Inquiry |
ITGA4-4998H | Recombinant Human ITGA4 Protein | +Inquiry |
ITGA4-4997H | Recombinant Human ITGA4 Protein, GST-tagged | +Inquiry |
ITGA4-4637M | Recombinant Mouse ITGA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Itga4-1696M | Recombinant Mouse Itga4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ITGA4-5133HCL | Recombinant Human ITGA4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All ITGA4 Products
Required fields are marked with *
My Review for All ITGA4 Products
Required fields are marked with *
0
Inquiry Basket