Active Recombinant Human JAK3 Protein, Flag tagged

• Cat.No.: JAK3-03H
• Product Overview: Recombinant JAK3 (781-1124) protein that includes amino acids 781-1124 of human JAK3 protein (accession number NP_000206.2) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Flag
• Protein Length: 781-1124 aa
• Description: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
• Form: 25 mM HEPESNaOH pH 7.5, 500 mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5 mM TCEP.
• Molecular Mass: 39.8 kDa
• Purity: > 80%
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Gene Information

• Gene Name: JAK3 Janus kinase 3 [ Homo sapiens (human) ]
• Official Symbol: JAK3
• Synonyms: JAK3; Janus kinase 3; tyrosine-protein kinase JAK3; JAK 3; JAK3_HUMAN; JAKL; L JAK; leukocyte Janus kinase; LJAK; tyrosine protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); JAK-3; L-JAK
• Gene ID: 3718
• mRNA Refseq: NM_000215
• Protein Refseq: NP_000206
• MIM: 600173
• UniProt ID: P52333