Active Recombinant Human NPR1 protein, mFc-tagged, Low Endotoxin

• Cat.No.: NPR1-0539H
• Product Overview: Recombinant Human NPR1 protein(NP_000897.3)(Gly33-Glu473), fused with C-terminal mFc tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: mFc
• Protein Length: 33-473 aa
• Form: Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Bio-activity: Immobilized Human NPR1, mFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-NPR1 Antibody, hFc Tag with the EC50 of 43.2ng/ml determined by ELISA.
• Molecular Mass: The protein has a predicted MW of 74.56 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.01 EU per μg by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC
• Storage: Store at -20 to -80°C for 24 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
• Reconstitution: Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) [ Homo sapiens ]
• Official Symbol: NPR1
• Synonyms: NPR1; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A); ANPRA, NPRA; atrial natriuretic peptide receptor 1; ANPa; GUCY2A; GC-A; ANP-A; NPR-A; ANPR-A; guanylate cyclase A; natriuretic peptide receptor A; atrionatriuretic peptide receptor A; natriuretic peptide A type receptor; atrial natriuretic peptide receptor type A; NPRA; ANPRA; GUC2A
• Gene ID: 4881
• mRNA Refseq: NM_000906
• Protein Refseq: NP_000897
• MIM: 108960
• UniProt ID: P16066