Active Recombinant Human NRG1 Protein, His-tagged

• Cat.No.: NRG1-11129H
• Product Overview: Active Recombinant Human NRG1 Protein(Q02297-6)(Ser177-Glu241) is expressed from HEK293 with His tag at the N-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 177-241 aa
• Form: Lyophilized from 0.22 μm filtered solution in 50mM NaAc, 150mM NaCl (pH 5.0).
• Bio-activity: Immobilized Human NRG1 Beta 1, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human Her3, hFc Tag with the EC50 of 35.8ng/ml determined by ELISA.
• Molecular Mass: The protein has a predicted MW of 8.57 kDa. Due to glycosylation, the protein migrates to 10-13 kDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 1 EU per μg by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
• Reconstitution: Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: NRG1 neuregulin 1 [ Homo sapiens ]
• Official Symbol: NRG1
• Synonyms: NRG1; neuregulin 1; HGL; pro-neuregulin-1, membrane-bound isoform; GGF; HRG; NDF; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; neuregulin 1 type IV beta 3; neuregulin 1 type IV beta 1a; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator); ARIA; GGF2; HRG1; HRGA; SMDF; MST131
• Gene ID: 3084
• mRNA Refseq: NM_001159995
• Protein Refseq: NP_001153467
• MIM: 142445
• UniProt ID: Q02297