Active Recombinant Human PDGFRB protein, hFc&His-tagged

• Cat.No.: PDGFRB-2657H
• Product Overview: Active Recombinant Human PDGFR-beta/CD140b(E241D) Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu33-Phe530 (Glu241Asp)) of human PDGFRB/CD140b (Accession #NP_002600.1) fused with an Fc, 6×His tag at the C-terminus.

Specification

• Source: HEK293
• Species: Human
• Tag: hFc&His
• Form: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized recombinant Human PDGF-B at 2 μg/mL (100 μL/well) can bind recombinant Human PDGFRB. The EC50 of Human PDGFRB is 30.48 ng/mL.
• Molecular Mass: 110-140 kDa
• Protein Length: Leu33-Phe530 (Glu241Asp)
• Endotoxin: < 0.1 EU/μg of the protein by LAL method.
• Purity: > 90% by SDS-PAGE.
• Storage: Store the lyophilized protein at -20°C to -80 °C for long term.
  After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
• Reconstitution: Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

Gene Information

• Gene Name: PDGFRB platelet-derived growth factor receptor, beta polypeptide [ Homo sapiens ]
• Official Symbol: PDGFRB
• Synonyms: PDGFRB; platelet-derived growth factor receptor, beta polypeptide; PDGFR; platelet-derived growth factor receptor beta; CD140b; JTK12; PDGFR1; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta-type platelet-derived growth factor receptor; CD140B; PDGFR-1
• Gene ID: 5159
• mRNA Refseq: NM_002609
• Protein Refseq: NP_002600
• MIM: 173410
• UniProt ID: P09619