Active Recombinant Human RSPO1 Protein, Pre-aliquoted
Cat.No. : | RSPO1-28H |
Product Overview : | Recombinant Human RSPO1 Protein, Arg31 - Ala263, was expressed in CHO. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. |
Source : | CHO |
Species : | Human |
Bio-activity : | Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 1.0-4.0 ng/mL in the presence of 5 ng/mL Recombinant Mouse Wnt‑3a. |
Molecular Mass : | Predicted Molecular Mass:25.6 kDa SDS-PAGE: 39 kDa, reducing conditions |
Protein length : | Arg31-Ala263 |
N-terminal Sequence Analysis : | Ser21 & Arg31 |
Endotoxin : | < 0.10 EU/μg of the protein by the LAL method. |
Purity : | > 90% by SDS-PAGE under reducing conditions and visualized by silver stain. |
Stability : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. • 6 months from date of receipt at room temperature as supplied. • 12 months from date of receipt at 2-8 centigrade as supplied. • 1 month at 2-8 centigrade under sterile conditions after reconstitution. • 3 months at -20 to -80 centigrade under sterile conditions after reconstitution. |
Reconstitution : | For a stock solution, reconstitute at 100 μg/mL in sterile PBS. For immediate use, simply roll Pre-aliquoted directly into cell culture medium. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | RSPO1 R-spondin 1 [ Homo sapiens (human) ] |
Official Symbol : | RSPO1 |
Synonyms : | RSPO1; R-spondin 1; RSPO; CRISTIN3; R-spondin-1; R-spondin homolog; roof plate-specific spondin-1 |
Gene ID : | 284654 |
mRNA Refseq : | NM_001038633 |
Protein Refseq : | NP_001033722 |
MIM : | 609595 |
UniProt ID : | Q2MKA7 |
Products Types
◆ Recombinant Protein | ||
RSPO1-421H | Recombinant Human RSPO1 Protein, His-tagged | +Inquiry |
RSPO1-132H | Active Recombinant Human RSPO1 Protein (Ser21-Ala263), N-His-SUMO tagged, Animal-free, Carrier-free | +Inquiry |
RSPO1-34H | Recombinant Human RSPO1 Protein | +Inquiry |
Rspo1-8672M | Active Recombinant Mouse Rspo1 protein(Met1-Gln265), His-tagged | +Inquiry |
RSPO1-422H | Recombinant Human RSPO1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
RSPO1-1918HCL | Recombinant Human RSPO1 cell lysate | +Inquiry |
RSPO1-001MCL | Recombinant Mouse RSPO1 cell lysate | +Inquiry |
RSPO1-001HCL | Recombinant Human RSPO1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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