Active Recombinant Human SEMA7A Protein, Fc Chimera

• Cat.No.: SEMA7A-1031H
• Product Overview: Recombinant Human SEMA7A (Accession # O75326), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: His47
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When recombinant human Plexin-C1 is coated at 5 µg/mL, recombinant human Semaphorin 7A/Fc Chimera binds with an apparent KD < 5 nM.
• Molecular Mass: Recombinant Human SEMA7A, Fc Chimera has a calculated MW of 94.8 kDa (monomer). In SDS-PAGE migrates as 100-105 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 100 µg/mL in sterile, deionized water.

Gene Information

• Gene Name: SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) [ Homo sapiens ]
• Official Symbol: SEMA7A
• Synonyms: SEMA7A; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A , sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group) , SEMAL; semaphorin-7A; CD108; H Sema K1; H Sema L; John Milton Hagen blood group; sema L; sema K1; semaphorin L; semaphorin-L; semaphorin K1; semaphorin-K1; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); JMH; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1; MGC126692; MGC126696
• Gene ID: 8482
• mRNA Refseq: NM_001146029
• Protein Refseq: NP_001139501
• UniProt ID: O75326
• Chromosome Location: 15q22.3-q23