Active Recombinant Human STK3, GST-tagged
Cat.No. : | STK3-1486H |
Product Overview : | Recombinant full-length human STK3 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | STK3, also known as MST2, encodes a protein of 491-amino acid which contains an N-terminal catalytic domain characteristic of STKs. STK3 and STK4 share 94% amino acid identity in the catalytic domain and 78% identity overall. RAF1 has been shown to counteract apoptosis by suppressing the activation of mammalian sterile 20-like kinase (MST2). STK3 is a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand. STK3 activation presumably allows cells to resist unfavorable environmental conditions. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 277 nmol/min/mg |
Molecular Mass : | ~87 kDa |
Protein length : | Full length |
Purity : | >80% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | STK3 serine/threonine kinase 3 [ Homo sapiens ] |
Official Symbol : | STK3 |
Synonyms : | STK3; serine/threonine kinase 3; serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine-protein kinase 3; KRS1; MST2; MST-2; STE20-like kinase MST2; mammalian STE20-like protein kinase 2; serine/threonine-protein kinase Krs-1; serine/threonine kinase 3 (STE20 homolog, yeast); FLJ90748; |
Gene ID : | 6788 |
mRNA Refseq : | NM_001256312 |
Protein Refseq : | NP_001243241 |
MIM : | 605030 |
UniProt ID : | Q13188 |
Chromosome Location : | 8q22.2 |
Pathway : | MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Signal Transduction, organism-specific biosystem; Signaling by Hippo, organism-specific biosystem; |
Function : | ATP binding; ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein dimerization activity; protein kinase activity; protein kinase activity; protein serine/threonine kinase activator activity; protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
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STK3-8805M | Recombinant Mouse STK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
STK3-1231H | Recombinant Human STK3 Protein (M1-F491), Tag Free | +Inquiry |
STK3-4343R | Recombinant Rhesus Macaque STK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
STK3-1405HCL | Recombinant Human STK3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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