Recombinant Human Serine/threonine Kinase 3 (STE20 Homolog, Yeast)

• Cat.No.: STK3-731H
• Product Overview: Recombinant Human MST2, full length, amino acids M1-F491, untagged, expressed inSf9insect cells. MW = 56,884 Da.

Specification

• Cat. No.: STK3-731H
• Description: Serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the STK3 gene. Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions.
• Source: Baculovirus infected Sf9 cells.
• Purification: GST-Affinity Chromatography followed by 3C mediated removal of the GST tag.
• Product Identity: MST2 was confirmed as MST2 by mass spectroscopy LC-ESI-MS/MS.
• Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 20% glycerol.
• Concentration: 0.271 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
• Specific Activity: 47 pmol/μg×min.
• Storage: -80°C. Avoid repeated freeze-thaw cycles!

Gene Information

• Gene Name: STK3 serine/threonine kinase 3 (STE20 homolog, yeast) [ Homo sapiens ]
• Synonyms: STK3; serine/threonine kinase 3 (STE20 homolog, yeast); KRS1; MST2; FLJ90748; serine/threonine kinase 3; serine/threonine kinase 3 (Ste20, yeast homolog); EC 2.7.11.1; MST-2; Mammalian STE20-like protein kinase 2; STE20-like kinase MST2; Serine/threonine-protein kinase Krs-1; Serine/threonine-protein kinase 3
• Gene ID: 6788
• mRNA Refseq: NM_006281
• Protein Refseq: NP_006272
• MIM: 605030
• UniProt ID: Q13188
• Chromosome Location: 8q22.2
• Pathway: MAPK signaling pathway
• Function: ATP binding; magnesium ion binding; nucleotide binding; protein dimerization activity; protein serine/threonine kinase activity; transferase activity