Active Recombinant Human TNF protein, APC labeled
Cat.No. : | TNF-242HA |
Product Overview : | Recombinant Human TNF was expressed in E. coli and labeled with APC in vitro. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
Source : | E. coli |
Species : | Human |
Tag : | Tag Free |
Form : | Solution |
Bio-activity : | ED50 is less or equal to 0.2 ng/mL as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D. |
Molecular Mass : | 17.5 kDa before labeling |
Purity : | > 95 % as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Concentration : | 1.0 mg/mL |
Gene Name : | TNF tumor necrosis factor [ Homo sapiens (human) ] |
Official Symbol : | TNF |
Synonyms : | TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; tumor necrosis factor; APC1 protein; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha; tumor necrotic factor alpha |
Gene ID : | 7124 |
mRNA Refseq : | NM_000594 |
Protein Refseq : | NP_000585 |
MIM : | 191160 |
UniProt ID : | P01375 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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