Active Recombinant Human TNF protein, APC labeled

• Cat.No.: TNF-242HA
• Product Overview: Recombinant Human TNF was expressed in E. coli and labeled with APC in vitro.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor
  necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It
  can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and
  TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of
  biological processes including cell proliferation, differentiation, apoptosis, lipid
  metabolism, and coagulation. This cytokine has been implicated in a variety of diseases,
  including autoimmune diseases, insulin resistance, and cancer. Knockout studies in
  mice also suggested the neuroprotective function of this cytokine.
• Form: Solution
• Bio-activity: ED50 is less or equal to 0.2 ng/mL as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D.
• Molecular Mass: 17.5 kDa before labeling
• Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining
• Storage: Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Concentration: 1.0 mg/mL
• Conjugation: APC

Gene Information

• Gene Name: TNF tumor necrosis factor [ Homo sapiens (human) ]
• Official Symbol: TNF
• Synonyms: TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; tumor necrosis factor; APC1 protein; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha; tumor necrotic factor alpha
• Gene ID: 7124
• mRNA Refseq: NM_000594
• Protein Refseq: NP_000585
• MIM: 191160
• UniProt ID: P01375