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Active Recombinant Human TNFRSF17 Protein, Fc-tagged, Atto 488 conjugated

Cat.No. : TNFRSF17-03H
Product Overview : Recombinant human Atto 488 conjugated BCMA/TNFRSF17 (Met1-Ala54) protein with a human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in mouse myeloma cell line.
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Description : The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Source : Mouse myeloma cell line
Species : Human
Tag : Fc
Form : Disulfide-linked homodimer
Labeled with Atto 488 via amines
Excitation Wavelength: 501 nm
Emission Wavelength: 523 nm
Bio-activity : Measured by flow cytometry for its ability to bind anti-Human BCMA Monoclonal Antibody conjugated fluorescent beads.
Molecular Mass : 32 kDa
N-terminal Sequence Analysis : Met1
Endotoxin : <1.0 EU/μg of the protein by the LAL method.
Purity : >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage : Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after opening.
3 months, -20 to -70 centigrade under sterile conditions after opening.
Storage Buffer : Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping : The product is shipped with dry ice or equivalent.
Gene Name : TNFRSF17 TNF receptor superfamily member 17 [ Homo sapiens (human) ]
Official Symbol : TNFRSF17
Synonyms : TNFRSF17; TNF receptor superfamily member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B cell maturation antigen; B-cell maturation factor; B-cell maturation protein
Gene ID : 608
mRNA Refseq : NM_001192
Protein Refseq : NP_001183
MIM : 109545
UniProt ID : Q6PE46

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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