Active Recombinant Human TNFRSF17 Protein, Fc-tagged, FITC conjugated
Cat.No. : | TNFRSF17-2070HF |
Product Overview : | FITC conjugated recombinant human TNFRSF17 is produced inHEK 293 Cellswith the C-terminus to the Fc portion of human IgG1. MW=42kDa. |
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Description : | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Bio-activity : | Blocks the binding of BAFF and APRIL to their receptors BCMA and TACI, inhibiting BAFF- and APRIL-mediated B cell activation. |
Endotoxin : | < 0.1 EU/ μg purified protein (LAL test; BioWhittaker). |
Purity : | ≥95 % by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
Applications : | Flow Cytometry: Detection of membrane-bound mouse BAFF and human APRIL in combination with fluorescently labelled Ab to IgG1. |
Storage : | Stable for at least 6 months after receipt when stored at -20 centigrade. Avoid freeze/thaw cycles. |
Concentration : | 1 mg/mL |
Storage Buffer : | Contains PBS. |
Reconstitution : | Reconstitute with 50 μl of sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. |
Gene Name : | TNFRSF17 tumor necrosis factor receptor superfamily, member 17 [ Homo sapiens ] |
Official Symbol : | TNFRSF17 |
Synonyms : | TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF17; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B-cell maturation protein |
Gene ID : | 608 |
mRNA Refseq : | NM_001192 |
Protein Refseq : | NP_001183 |
MIM : | 109545 |
UniProt ID : | Q02223 |
Products Types
◆ Recombinant Protein | ||
TNFRSF17-5253H | Recombinant Human TNFRSF17 Protein | +Inquiry |
TNFRSF17-240H | Active Recombinant Human TNFRSF17 Protein, His-Avi-tagged, Biotinylated | +Inquiry |
TNFRSF17-100R | Recombinant Rhesus macaque TNFRSF17 Protein, Fc-tagged | +Inquiry |
TNFRSF17-02H | Active Recombinant Human TNFRSF17 Protein, Fc-tagged, Alexa Fluor® 647 conjugated | +Inquiry |
TNFRSF17-03H | Active Recombinant Human TNFRSF17 Protein, Fc-tagged, Atto 488 conjugated | +Inquiry |
◆ Lysates | ||
TNFRSF17-1489RCL | Recombinant Rat TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-2489HCL | Recombinant Human TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-1253CCL | Recombinant Cynomolgus TNFRSF17 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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