Active Recombinant Human TNFSF4 protein, mFc-tagged
Cat.No. : | TNFSF4-344H |
Product Overview : | Recombinant Human TNFSF4 protein(Gln 51 - Leu 183), fused with mFc tag, was expressed in HEK293. |
Availability | February 17, 2025 |
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Source : | HEK293 |
Species : | Human |
Tag : | mFc |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Bio-activity : | Immobilized Human OX40, Fc Tag at 0.5 μg/mL (100 μL/well) can bind Human OX40 Ligand Protein, Mouse IgG2a Fc Tag with a linear range of 0.8-13 ng/mL. |
Molecular Mass : | This protein carries a mouse IgG2a Fc tag at the C-terminus.The protein has a calculated MW of 42.3 kDa. The protein migrates as 53-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gln 51 - Leu 183 |
Endotoxin : | Less than 0.1 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 [ Homo sapiens ] |
Official Symbol : | TNFSF4 |
Synonyms : | TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; tax transcriptionally activated glycoprotein 1, 34kD , TXGP1; tumor necrosis factor ligand superfamily member 4; CD252; gp34; OX 40L; OX40L; CD134 ligand; glycoprotein Gp34; OX40 antigen ligand; TAX transcriptionally-activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 (34kD); GP34; OX4OL; TXGP1; CD134L; OX-40L; |
Gene ID : | 7292 |
mRNA Refseq : | NM_003326 |
Protein Refseq : | NP_003317 |
MIM : | 603594 |
UniProt ID : | P23510 |
Products Types
◆ Recombinant Protein | ||
TNFSF4-5150H | Recombinant Human TNFSF4 protein, His-Flag-tagged | +Inquiry |
TNFSF4-690M | Recombinant Mouse TNFSF4 Protein, Fc-tagged | +Inquiry |
TNFSF4-5861R | Recombinant Rat TNFSF4 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF4-491H | Recombinant Human TNFSF4 protein, hFc-Flag-tagged | +Inquiry |
TNFSF4-886M | Recombinant Mouse TNFSF4 Protein (Gln49-Leu198), MIgG1 Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFSF4-857CCL | Recombinant Cynomolgus TNFSF4 cell lysate | +Inquiry |
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Q&As (7)
Ask a questionGenetic changes in TNFSF4 affect immune regulation and autoimmune disease susceptibility.
TNFSF4 (OX40L) regulates immune responses and T-cell activation.
It activates T-cells, stimulating inflammatory cytokine production.
TNFSF4 is implicated in autoimmune disease development by promoting immune cell activation.
TNFSF4 interacts with OX40 and other receptors, influencing immune signaling.
Targeting TNFSF4 could treat autoimmune and inflammatory diseases by modulating the immune system.
Altered TNFSF4 activity contributes to chronic inflammation.
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