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Active Recombinant Human TNFSF4 protein, mFc-tagged

Cat.No. : TNFSF4-344H
Product Overview : Recombinant Human TNFSF4 protein(Gln 51 - Leu 183), fused with mFc tag, was expressed in HEK293.
Availability February 17, 2025
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Source : HEK293
Species : Human
Tag : mFc
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Bio-activity : Immobilized Human OX40, Fc Tag at 0.5 μg/mL (100 μL/well) can bind Human OX40 Ligand Protein, Mouse IgG2a Fc Tag with a linear range of 0.8-13 ng/mL.
Molecular Mass : This protein carries a mouse IgG2a Fc tag at the C-terminus.The protein has a calculated MW of 42.3 kDa. The protein migrates as 53-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : Gln 51 - Leu 183
Endotoxin : Less than 0.1 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 [ Homo sapiens ]
Official Symbol : TNFSF4
Synonyms : TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; tax transcriptionally activated glycoprotein 1, 34kD , TXGP1; tumor necrosis factor ligand superfamily member 4; CD252; gp34; OX 40L; OX40L; CD134 ligand; glycoprotein Gp34; OX40 antigen ligand; TAX transcriptionally-activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 (34kD); GP34; OX4OL; TXGP1; CD134L; OX-40L;
Gene ID : 7292
mRNA Refseq : NM_003326
Protein Refseq : NP_003317
MIM : 603594
UniProt ID : P23510

Not For Human Consumption!

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12/28/2022

    Efficient service, accelerates research productivity.

    05/13/2018

      Outstanding accuracy, essential for research quality.

      02/12/2018

        Trusted for research integrity, a critical research asset.

        Q&As (7)

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        How do genetic variations in TNFSF4 affect immune function? 01/09/2022

        Genetic changes in TNFSF4 affect immune regulation and autoimmune disease susceptibility.

        What is the primary role of TNFSF4 in immune system regulation? 08/16/2021

        TNFSF4 (OX40L) regulates immune responses and T-cell activation.

        How does TNFSF4 contribute to inflammatory responses? 05/11/2020

        It activates T-cells, stimulating inflammatory cytokine production.

        What role does TNFSF4 play in autoimmune disorders? 09/12/2019

        TNFSF4 is implicated in autoimmune disease development by promoting immune cell activation.

        How does TNFSF4 interact with other cytokines and receptors in the immune system? 06/09/2019

        TNFSF4 interacts with OX40 and other receptors, influencing immune signaling.

        What potential therapeutic applications arise from targeting TNFSF4 in immune-related diseases? 10/04/2018

        Targeting TNFSF4 could treat autoimmune and inflammatory diseases by modulating the immune system.

        What is the impact of altered TNFSF4 activity on chronic inflammation? 03/29/2017

        Altered TNFSF4 activity contributes to chronic inflammation.

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