Active Recombinant Mouse Bace1 protein(Met1-Thr457), His-tagged
Cat.No. : | Bace1-252M |
Product Overview : | Recombinant Mouse Bace1 protein(NP_035922.4)(Met1-Thr457), fused with C-terminal His tag, was expressed in HEK293. |
Availability | October 24, 2024 |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
- Download
similar : | Bace1 |
Alias : | BACE1; beta-site APP cleaving enzyme 1; beta-secretase 1; ASP2; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; membrane-associated aspartic protease 2; beta-site amyloid precursor protein cleaving enzyme 1; C76936; |
Source : | HEK293 |
Species : | Mouse |
Conjugate : | C-His |
Tag : | His |
Protein length : | Met1-Thr457 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
MolecularMass : | The secreted recombinant mouse BACE1 consists of 447 amino acids and has a calculated molecular mass of 49.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
GeneName : | Bace1 beta-site APP cleaving enzyme 1 [ Mus musculus ] |
GeneNameWeblink : | 23821 |
OfficialSymbol : | Bace1 |
OfficialSymbolWeblink : | 23821 |
GeneIDWeblink : | 23821 |
mRNARefseq : | NM_001145947 |
mRNARefseqWeblink : | NM_001145947.1 |
ProteinRefseqWeblink : | NP_001139419.1 |
Synonyms : | BACE1; beta-site APP cleaving enzyme 1; beta-secretase 1; ASP2; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; membrane-associated aspartic protease 2; beta-site amyloid precursor protein cleaving enzyme 1; C76936; |
Gene ID : | 23821 |
Synonyms : | BACE1; beta-site APP cleaving enzyme 1; beta-secretase 1; ASP2; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; membrane-associated aspartic protease 2; beta-site amyloid precursor protein cleaving enzyme 1; C76936; |
Gene ID : | 23821 |
Products Types
◆ Recombinant Protein | ||
BACE1-587R | Recombinant Rat BACE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BACE1-331R | Recombinant Rhesus Macaque BACE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Bace1-1815M | Recombinant Mouse Bace1 Protein, Myc/DDK-tagged | +Inquiry |
BACE1-780H | Recombinant Human BACE1 Protein, Fc-tagged | +Inquiry |
BACE1-2200H | Recombinant Human BACE1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
BACE1-3006HCL | Recombinant Human BACE1 cell lysate | +Inquiry |
BACE1-3077MCL | Recombinant Mouse BACE1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewSuch support ensures researchers have access to reliable tools and expertise, facilitating their investigations into the functions, mechanisms, and disease relevance of BACE1 protein.
A manufacturer can serve as a collaborative partner, engaging in discussions, and exchanging knowledge with researchers.
Using BACE1 protein in trials provides advantages such as its involvement in cellular processes and its disease associations.
Q&As (5)
Ask a questionYes, several clinical trials are underway to assess the safety and efficacy of BACE1 inhibitors in treating Alzheimer's disease.
BACE1 is implicated in Alzheimer's disease as it initiates the cleavage of APP, leading to the formation of beta-amyloid plaques, a hallmark of the disease.
BACE1 inhibitors may slow down or prevent the accumulation of beta-amyloid plaques, potentially delaying the progression of Alzheimer's disease.
Yes, several clinical trials are underway to assess the safety and efficacy of BACE1 inhibitors in treating Alzheimer's disease.
Yes, BACE1 inhibitors are being explored as potential therapeutic agents for Alzheimer's disease to reduce the production of beta-amyloid peptides.
Ask a Question for All Bace1 Products
Required fields are marked with *
My Review for All Bace1 Products
Required fields are marked with *
Inquiry Basket