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Active Recombinant Mouse Ccl2 Protein

Cat.No. : Ccl2-130M
Product Overview : Purified recombinant protein of Mouse chemokine (C-C motif) ligand 2 (Ccl2) without tag was expressed in E.coli.
  • Specification
  • Gene Information
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Description : This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis.
Source : E. coli
Species : Mouse
Bio-activity : Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.
Molecular Mass : 13.8 kDa
AA Sequence : QPDAVNAPLTCCYSFTSKMIPMSRL ESYKRITSSRCPKEAVVFVTKLKRE VCADPKKEWVQTYIKNLDRNQMRSE PTTLFKTASALRSSAPLNVKLTRKS EANASTTFSTTTSSTSVGVTSVTVN
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Purity : >95%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Storage : Store at -80 centigrade.
Storage Buffer : Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Reconstitution : Resuspend the protein in the desired concentration in proper buffer.
Gene Name : Ccl2 chemokine (C-C motif) ligand 2 [ Mus musculus (house mouse) ]
Official Symbol : Ccl2
Synonyms : Ccl2; chemokine (C-C motif) ligand 2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594; C-C motif chemokine 2; monocyte chemoattractant protein 1; monocyte chemotactic protein 1; platelet-derived growth factor-inducible protein JE; small-inducible cytokine A2
Gene ID : 20296
mRNA Refseq : NM_011333
Protein Refseq : NP_035463
UniProt ID : P10148

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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