Active Recombinant Mouse Csf2

• Cat.No.: Csf2-9789M
• Product Overview: Recombinant Mouse Csf2 was expressed in CHO Cells.

Specification

• Species: Mouse
• Source: CHO
• Tag: Non
• Description: Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils.
• Form: Lyophilized after extensive dialysis against PBS.
• Bio-activity: ED50< 0.05="" ng/ml,="" measured="" in="" a="" cell="" proliferation="" assay="" using="" mouse="" fdc-p1="" cells,="" corresponding="" to="" a="" specific="" activity="" of="">2 x 107 units/mg.
• Molecular Mass: 15~19 kDa, observed by non-reducing SDS-PAGE.
• AA Sequence: A18-K141
• Endotoxin: <0.2 eu/μg,="" determined="" by="" lal="">
• Purity: >95% as analyzed by SDS-PAGE and HPLC.
• Storage: Lyophilized recombinant protein remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmGM-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
• Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/ml.

Gene Information

• Gene Name: Csf2 colony stimulating factor 2 (granulocyte-macrophage) [ Mus musculus ]
• Official Symbol: Csf2
• Synonyms: CSF2; colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; CSF; put. GM-CSF; colony-stimulating factor; granulocyte-macrophage colony stimulating factor 2; Csfgm; GMCSF; Gm-CSf; MGI-IGM; MGC151255; MGC151257
• Gene ID: 12981
• mRNA Refseq: NM_009969
• Protein Refseq: NP_034099
• UniProt ID: Q14AD9
• Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response (BioCarta), organism-specific biosystem; Fc epsilon RI signaling pathway, organism-specific biosystem
• Function: cytokine activity; cytokine activity; granulocyte macrophage colony-stimulating factor receptor binding; growth factor activity