Active Recombinant Mouse Cx3cl1 Protein, His-tagged

Cat.No. : Cx3cl1-951M
Product Overview : Recombinant Mouse Cx3cl1 (Accession # O35188) Gln25-Arg337, fused with a C-terminal 6-His tag, was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived.
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Source : Baculovirus Sf21 Insect Cells
Species : Mouse
Tag : His
Predicted N Terminal : No results obtained: Gln25 predicted
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to chemoattract freshly isolated human peripheral blood lymphocytes (PBL).The ED50 for this effect is typically 0.2 - 0.6 µg/mL.Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CX3CR1.The ED50 for this effect is typically 0.03 - 0.12 µg/mL.
Molecular Mass : Recombinant Mouse Cx3cl1, His-tagged has a calculated MW of 34 kDa. In SDS-PAGE migrates as 90 kDa, reducing conditions.
Protein length : Gln25-Arg337
Purity : >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : Cx3cl1 chemokine (C-X3-C motif) ligand 1 [ Mus musculus ]
Official Symbol : Cx3cl1
Synonyms : CX3CL1; chemokine (C-X3-C motif) ligand 1; fractalkine; neurotactin; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D, 1; CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747; D8Bwg0439e;
Gene ID : 20312
mRNA Refseq : NM_009142
Protein Refseq : NP_033168
MIM :

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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In what ways is CX3CL1 linked to the modulation of pain perception and neuropathic pain conditions? 04/30/2021

CX3CL1 is involved in pain modulation, and its dysregulation is associated with neuropathic pain conditions. Understanding its role may lead to the development of novel analgesic therapies.

Are there any ongoing clinical trials targeting CX3CL1 for therapeutic purposes? 09/14/2020

Yes, several clinical trials are investigating the therapeutic potential of targeting CX3CL1 in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

In cardiovascular diseases, how does CX3CL1 impact inflammation and vascular function? 03/23/2020

CX3CL1 contributes to inflammation in cardiovascular diseases and affects vascular function. Studying its role helps in understanding the pathophysiology of conditions like atherosclerosis.

How does CX3CL1 influence the recruitment and activation of immune cells in the context of inflammation? 01/06/2019

CX3CL1 acts as a chemoattractant, facilitating the recruitment and activation of immune cells at the site of inflammation, playing a pivotal role in immune response regulation.

How is CX3CL1 being investigated for its potential as a biomarker in various diseases? 05/19/2016

Researchers are exploring CX3CL1 as a potential biomarker for diseases such as rheumatoid arthritis and certain cancers, aiming to develop diagnostic tools and monitor disease progression.

Customer Reviews (3)

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Reviews
03/15/2022

    the CX3CL1 protein's compatibility with various experimental techniques further supports its usability.

    08/06/2021

      One of the standout features of the CX3CL1 protein is the excellent technical support provided by the manufacturer.

      06/03/2021

        Whether I need to study protein-protein interactions, protein localization, or protein folding, the CX3CL1 protein consistently delivers precise and meaningful data.

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