"IFNGR1" Related Products

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Recombinant Human IFNGR1 Protein, His-tagged

Cat.No.: IFNGR1-001H
Product Overview: Recombinant human IFNGR1(18-245aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description: IFNGR1, also known as interferon gamma receptor 1, is a member of the hematopoietic cytokine receptor superfamily. It is a receptor that binds interferon-γ, the sole member of interferon type II. It induces the rapid dimerization of chains, thereby forming a site that is recognized by the extracellular domain of IFNGR2. It is expressed in a membrane-bound form in many cell types, and is over-expressed in tumour cells. Its signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. It is crucial for host defence against mycobacterial infections. It is associated with susceptibility to pulmonary tuberculosis (TB).
Source: Insect cell
Species: Human
Tag : His
Form: Liquid
Molecular Mass: 26.6 kDa
AASequence: EMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVEVKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEKQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGHHHHHH
N-terminal Sequence Analysis: Glu 18
Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method)
Purity: > 90% by SDS - PAGE
Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 1.0 mg/mL (determined by Absorbance at 280nm)
Storage Buffer: In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Warning: For research use only. This product is not intended or approved for human, diagnostics or veterin
Gene Name: IFNGR1 interferon gamma receptor 1 [ Homo sapiens (human) ]
Official Symbol: IFNGR1
Synonyms: IFNGR1; interferon gamma receptor 1; CD119; IFNGR; IMD27A; IMD27B;
Gene ID: 3459
mRNA Refseq: NM_000416
Protein Refseq: NP_000407
MIM: 107470
UniProt ID: P15260

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