Active Recombinant Mouse IGF1R Protein, His-tagged

• Cat.No.: IGF1R-22M
• Product Overview: Recombinant Mouse IGF1R Protein (Met1-His936) was expressed in CHO cells with C-terminal His tag. This protein is covalently-linked heterotetramers (2 alpha and 2 beta subunits) & covalently-linked single chain homodimers.

Specification

• Source: CHO
• Species: Mouse
• Tag: His
• Form: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Bio-activity: Measured by its binding ability in a functional ELISA. When rmIGF-IR is present at 0.5 μg/mL, the concentration of rmIGF-I that produces 50% of the optimal binding response is found to be approximately 25-100 ng/mL.
• Molecular Mass: 104.5 kDa (single chain), 80.7 kDa ( alpha subunit) & 23.2 kDa ( beta subunit)
• Endotoxin: <0.01 EU per 1 μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Storage: Storage at -20 to -70 centigrade.
• Reconstitution: Reconstitute at 100 μg/mL in PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: Igf1r insulin-like growth factor I receptor [ Mus musculus ]
• Official Symbol: IGF1R
• Synonyms: IGF1R; insulin-like growth factor I receptor; insulin-like growth factor 1 receptor; line 186; IGF-I receptor; hyft; CD221; IGF-1R; D930020L01; A330103N21Rik
• Gene ID: 16001
• mRNA Refseq: NM_010513
• Protein Refseq: NP_034643