Active Recombinant Mouse Il33 Protein (Ser109-Ile266), C-His tagged, Animal-free, Carrier-free
Cat.No. : | Il33-295M |
Product Overview : | Recombinant Mouse Il33 Protein (Ser109-Ile266) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 33 (IL-33) is a 17.65 kDa cytokine with 159 amino acid residues. IL-33 is a member of the IL-1 family and secreted from various cell types, such as mast cells, macrophages, endothelial cells, and epithelial cells. IL-33 activates NF-κB and MAPK signaling pathways that stimulate the secretion of type 2 cytokines like IL-5 and IL-13 when IL-33 binds to the ST2 receptor primarily expressed in mast cells and Th2 cells. In addition to Th type 2 responses, IL-33 participates in maintaining barrier tissue defense. |
Source : | E. coli |
Species : | Mouse |
Tag : | C-His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce proliferation in D10.G4.1 cells. The ED50 for this effect is < 40 pg/mL. The specific activity of recombinant mouse IL-33 is > 2 × 10⁷ IU/mg. |
Molecular Mass : | The protein has a calculated MW of 18.51 kDa. The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Ser109-Ile266 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | Il33 interleukin 33 [ Mus musculus (house mouse) ] |
Official Symbol : | Il33 |
Synonyms : | IL33; interleukin 33; interleukin-33; nuclear factor from high endothelial venules; Il-33; Il1f11; NF-HEV; 9230117N10Rik; |
Gene ID : | 77125 |
mRNA Refseq : | NM_001164724 |
Protein Refseq : | NP_001158196 |
UniProt ID : | Q8BVZ5 |
Products Types
◆ Recombinant Protein | ||
Il33-3521M | Recombinant Mouse Il33 Protein | +Inquiry |
IL33-2313H | Recombinant Human IL33 Protein, His-tagged | +Inquiry |
IL33-2700R | Recombinant Rat IL33 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL33-174H | Active Recombinant Human IL33 Protein | +Inquiry |
Il33-1679M | Recombinant Mouse Il33 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL33-5226HCL | Recombinant Human IL33 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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