Creative BioMart to Present at BPS 2025 Annual Meeting | February 15-19, 2025

Active Recombinant Mouse Mmp9 Protein (20-730aa), C-His-tagged

Cat.No. : Mmp9-03M
Product Overview : Recombinant mouse MMP-9 protein (20-730aa), fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mice lacking the encoded protein exhibit an abnormal pattern of skeletal growth plate vascularization and ossification, reduced keratinocyte hyperproliferation at all neoplastic stages, a decreased incidence of invasive tumors, and resistance to experimental autoimmune encephalomyelitis.
Source : HEK293
Species : Mouse
Tag : His
Form : Liquid
Bio-activity : > 1,500 pmol/min/μg, and is defined as the amount of enzyme that cleaves 1 pmol of Mca-PLGL-Dpa-AR-NH2 per minute at pH 7.5 at 25 centigrade.
Molecular Mass : 79.3 kDa (717aa)
Protein length : 20-730aa
AA Sequence : APYQRQPTFVVFPKDLKTSNLTDTQ LAEAYLYRYGYTRAAQMMGEKQSLR PALLMLQKQLSLPQTGELDSQTLKA IRTPRCGVPDVGRFQTFKGLKWDHH NITYWIQNYSEDLPRDMIDDAFARA FAVWGEVAPLTFTRVYGPEADIVIQ FGVAEHGDGYPFDGKDGLLAHAFPP GAGVQGDAHFDDDELWSLGKGVVIP TYYGNSNGAPCHFPFTFEGRSYSAC TTDGRNDGTPWCSTTADYDKDGKFG FCPSERLYTEHGNGEGKPCVFPFIF EGRSYSACTTKGRSDGYRWCATTAN YDQDKLYGFCPTRVDATVVGGNSAG ELCVFPFVFLGKQYSSCTSDGRRDG RLWCATTSNFDTDKKWGFCPDQGYS LFLVAAHEFGHALGLDHSSVPEALM YPLYSYLEGFPLNKDDIDGIQYLYG RGSKPDPRPPATTTTEPQPTAPPTM CPTIPPTAYPTVGPTVGPTGAPSPG PTSSPSPGPTGAPSPGPTAPPTAGS SEASTESLSPADNPCNVDVFDAIAE IQGALHFFKDGWYWKFLNHRGSPLQ GPFLTARTWPALPATLDSAFEDPQT KRVFFFSGRQMWVYTGKTVLGPRSL DKLGLGPEVTHVSGLLPRRLGKALL FSKGRVWRFDLKSQKVDPQSVIRVD KEFSGVPWNSHDIFQYQDKAYFCHG KFFWRVSFQNEVNKVDHEVNQVDDV GYVTYDLLQCP
Endotoxin : < 1 EU/μg of protein (determined by LAL method)
Purity : > 90% by SDS-PAGE
Applications : SDS-PAGE, Enzyme Activity
Notes : For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/mL (determined by Bradford assay)
Storage Buffer : Liquid in. 20mM Tris-HCl (pH 7.5) containing 1mM CaCl2, 100mM NaCl, 10% glycerol
Gene Name : Mmp9 matrix metallopeptidase 9 [ Mus musculus (house mouse) ]
Official Symbol : Mmp9
Synonyms : MMP9; matrix metallopeptidase 9; matrix metalloproteinase-9; GELB; Gel B; gelatinase B; 92kD gelatinase; 92kDa gelatinase; 92 kDa gelatinase; collagenase type IVB; 92kD type IV collagenase; 92kDa type IV collagenase; 92 kDa type IV collagenase; matrix metalloproteinase 9; Clg4b; MMP-9; B/MMP9; AW743869; pro-MMP-9;
Gene ID : 17395
mRNA Refseq : NM_013599
Protein Refseq : NP_038627
UniProt ID : P41245

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
05/03/2020

    The superior quality of this recombined protein has significantly enhanced the precision of our research outcomes.

    08/15/2019

      Fast shipping! Ordered this product, and it arrived well-packaged and ready for use in our experiments.

      01/21/2018

        Customer service went above and beyond to accommodate our specific needs, ensuring a smooth purchasing experience.

        Q&As (5)

        Ask a question
        What are the consequences of dysregulated MMP9 expression in cancer progression? 02/13/2022

        Dysregulated MMP9 expression is associated with cancer invasion and metastasis, as it enables tumor cells to degrade the extracellular matrix and invade surrounding tissues.

        What is the impact of MMP9 polymorphisms on enzyme activity? 09/07/2021

        Polymorphisms in the MMP9 gene can influence enzyme activity, potentially affecting the individual's susceptibility to certain diseases and the progression of pathological conditions.

        Can you explain the role of MMP9 in tissue remodeling at the molecular level? 01/17/2020

        MMP9 facilitates tissue remodeling by cleaving structural proteins in the extracellular matrix, such as collagen and gelatin, leading to changes in tissue architecture.

        What is the role of MMP9 in the breakdown of the blood-brain barrier during neurological disorders? 11/14/2019

        MMP9 contributes to the breakdown of the blood-brain barrier by degrading tight junction proteins, potentially exacerbating neurological disorders and neuroinflammation.

        How does MMP9 contribute to angiogenesis at the molecular level? 06/02/2018

        MMP9 plays a role in angiogenesis by promoting the release and activation of growth factors sequestered in the extracellular matrix, facilitating the formation of new blood vessels.

        Ask a Question for All Mmp9 Products

        Required fields are marked with *

        My Review for All Mmp9 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2025 Creative BioMart. All Rights Reserved.

        Contact Us

        • /
        • Service lnquiry:

        Stay Updated on the Latest Bioscience Trends