| Description : |
Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. |
| Source : |
Insect cell |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Lyophilized |
| Bio-activity : |
Since a ligand for TIE-1 has not yet been identified, the recombinant protein was not tested for biological activity. |
| Molecular Mass : |
95 kDa |
| AA Sequence : |
SVDLTLLANLRITDPQRFFLTCVSG EAGAGRSSDPPLLLEKDDRIVRTFP PGQPLYLARNGSHQVTLRGFSKPSD LVGVFSCVGGAGARRTRVLYVHNSP GAHLFPDKVTHTVNKGDTAVLSAHV HKKQTDVIWKNNGSYFNTLDWQEAD DGRFQLQLQNVQPPSSGIYSATYLE ASPLGSAFFRLIVRGCGAGRWGPGC VKDCPGCLHGGVCHDHDGECVCPPG FTGTRCEQACREGRFGQSCQEQCPG TAGCGLTFCLPDPYGCSCGSGWRGS QCQEACAPDHFGADCRLQCQCQNGG TCDRFSGCVCPSGWHGVHCEKSDRI PQILSMATEVEFNIGTMPRINCAAA GNPFPVRGSMKLRKPDGTMLLSTKV IVEPDRTAEFEVPSLTLGDSGFWEC RVSTSGGQDSRRFKVNVKVPPVPLT APRLLAKQSRQLVVSPLVSFSGDGP ISSVRLHYRPQDSTIAWSAIVVDPS ENVTLMNLKPKTGYNVRVQLSRPGE GGEGGWGPALMTTDCPEPLLQPWLE SWHVEGPDRLRVSWSLPSVPLSGDG FLLRLWDGARGQERRENISFPQART ALLTGLTPGTHYQLDVRLYHCTLLG PASPPAHVHLPPSGPPAPRHLHAQA LSDSEIQLMWHPEAPSGPISKYIVE IQVAGGSGDPQWMDVDRPEETSIIV RGLNASTRYLFRVRASVQGLGDWSN TVEEATLGNGLQSEDPVRESRATRH HHHHH |
| Endotoxin : |
< 0.1 ng/μg sTIE-1 |
| Purity : |
> 90 % |
| Stability : |
Samples are stable for 2-4 weeks at 2-8 centigrade. |
| Storage : |
sTIE-1 should be stored in working aliquots at -20 to -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Storage Buffer : |
PBS without stabilizers |
| Reconstitution : |
The lyophilized sTIE-1 is soluble in water and most aqueous buffers. The lyophilized sTIE-1 should be restored in PBS or medium to a concentration not lower than 50 μg/mL. |
