Active Recombinant Mouse VCAM1 Protein, MIgG2a mFc-tagged, Alexa Fluor 555 conjugated

• Cat.No.: VCAM1-1793MAF555
• Product Overview: The extracellular domain of mouse VCAM-1 (NP_035823.3) (Lys26-Glu698) (Alexa Fluor 555 conjugated) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.

Specification

• Description: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed bycytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion andsignal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Threealternatively spliced transcripts encoding different isoforms have been described for this gene
• Source: CHO
• Species: Mouse
• Tag: mFc
• Form: Lyophilized
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells.
• Molecular Mass: 100 kDa (monomer)
• AA Sequence: Lys26-Glu698
• Endotoxin: < 0.06 EU/ μg as determined by LAL test.
• Purity: > 98 % by SDS-PAGE under reducing conditions.
• Characteristic: Disulfide-linked homodimer
  Labeled with Alexa Fluor 555 via amines
  With an excitation and emission maximum of 555/565 nm, Alexa Fluor 555 can be efficiently excited using a 543 nm He-Ne laser line and detected under standard TRITC/Cy3 filters.
• Stability: Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade.
• Concentration: 100 μg/mL
• Storage Buffer: Lyophilized from 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.

Gene Information

• Gene Name: Vcam1 vascular cell adhesion molecule 1 [ Mus musculus ]
• Official Symbol: VCAM1
• Synonyms: VCAM1; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; V-CAM 1; CD106; Vcam-1
• Gene ID: 22329
• mRNA Refseq: NM_011693
• Protein Refseq: NP_035823