Active Recombinant Rat Eng, Fc Chimera

Species :	Rat
Source :	Mammalian Cells
Tag :	Fc
Predicted N Terminal :	Glu26
Form :	Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity :	Measured by its binding ability in a functional ELISA.When Recombinant Rat Endoglin/CD10^5 Fc Chimera is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.25-1.25 µg/mL.Measured by its ability to inhibit BMP-10-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells.The ED50 for this effect is typically 0.15-0.75 µg/mL.
Molecular Mass :	Recombinant Rat Eng, Fc Chimera has a calculated MW of 87.0 kDa (monomer). In SDS-PAGE migrates as 100-115 kDa, reducing conditions.
Purity :	>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage :	Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Name	Eng endoglin [ Rattus norvegicus ]
Official Symbol	Eng
Synonyms	ENG; endoglin; MGC124909;
Gene ID	497010
mRNA Refseq	NM_001010968
Protein Refseq	NP_001010968
MIM