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CD19 protein-coupled magnetic beads

Cat.No. : CD19-005M
Product Overview : The biotinylated CD19 protein was conjugated to streptavidin magnetic beads. This pre-coupled magnetic bead product can capture the anti-CD19 antibody from various assay systems. The beads are in uniform size, narrow size distribution with large surface area and unique surface coating, which can help you get the best performance and highly reproducible results. This CD19 coupled magnetic beads will bring great convenience with minimum non-specific binding and developed protocols. This ready-to-use product could greatly save your time and hassle.
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Species : Human
Beads Size : 2mg
Particle size : 2 μm
Beads Surface : hydrophilic
Coupled amount of protein : >300 nmol /mg Beads
Capacity : > 200 nmol antibody/ mg beads
Formulation : Lyophilized from 0.22 μm filtered solution in PBS, 0.05% Tween-20, pH7.4, with 10% Trehalose
Reconstitution : 2 mL ultrapure water (1mg beads/mL)
Application : This product is intended for immunocapture, biopanning and flow cytometry.
Storage : Upon receipt, please store the Beads at -20ºC for 1 year in lyophilized state. Once the Beads reconstitution, please use it immediately. Do not to freeze thaw the Beads after reconstitution.
Assay Principles : The conjugation was achieved by means of the binding between streptavidin and biotin. Streptavidin (SA) has an extraordinarily high affinity for biotin with a dissociation constant (Kd) on the order of 10-14 mol/L. Thus, the binding of streptavidin and biotin is irreversible. Our CD19 pre-coupled beads could capture anything binding to CD19, and make the following testing easy, such as immunocapture, biopanning and flow cytometry.
Application Method : a) Reconstitute the Beads following the COA. Wash and re-suspended the beads to a certain concentration by adding your dilution buffer.
b) Add the prepared beads to your samples.
c) Beads can be separated from your samples afterwards using a magnetic plate.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does CAR-T cell therapy work to combat CD19-expressing cancers? 02/11/2023

CAR-T cells are engineered to express a receptor that recognizes CD19 on the surface of cancerous B cells. When they encounter these cells, they destroy them.

Are there any diseases associated with CD19 dysfunction? 12/07/2022

CD19 deficiencies can lead to primary immunodeficiencies, making individuals more susceptible to infections.

What are the potential side effects of CAR-T cell therapy targeting CD19? 01/26/2022

Side effects may include cytokine release syndrome (CRS), neurologic toxicity, and long-term B-cell aplasia.

What are some CD19-expressing malignancies that CAR-T cell therapy can target? 07/17/2021

CAR-T cell therapy is used to treat B-cell malignancies such as acute lymphoblastic leukemia (ALL) and certain types of non-Hodgkin lymphoma.

How effective is CAR-T cell therapy in treating CD19-expressing cancers? 08/26/2019

CAR-T cell therapy has shown remarkable effectiveness in inducing remissions in patients with CD19-positive malignancies, particularly in those who have relapsed or failed conventional treatments.

Customer Reviews (3)

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Reviews
01/02/2023

    The manufacturer of CD19 protein has consistently provided outstanding technical support that has surpassed my expectations.

    08/18/2022

      This protein demonstrates remarkable purity, stability, and specificity, ensuring utmost accuracy and reproducibility in my research endeavors.

      06/29/2016

        Their dedication to customer satisfaction has been instrumental in overcoming obstacles and achieving successful results in my experiments.

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