Recombinant Human Transaldolase 1, His-tagged

• Cat.No.: TALDO1-2752H
• Product Overview: Recombinant human TALDO1, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW =39.7 kDa(357aa), confirmed by MALDI-TOF.

Specification

• Cat. No.: TALDO1-2752H
• Description: TALDO1 is a key enzyme of the non-oxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This protein transfers a dihydroxyacetone group from donor compounds (fructose 6-phosphate or sedoheptulose 7-phosphate) to aldehyde acceptor compounds. It is expressed at selectively high levels in oligodendrocytes of the brain. Deficiency of TALDO1 causes accumulation of erythritol, D-arabitol, and ribitol.
• Source: E.coli.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSSSPVKRQR MESALDQLKQ FTTVVADTGD FHAIDEYKPQ DATTNPSLIL AAAQMPAYQE LVEEAIAYGR KLGGSQEDQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA RARRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE AGVTLISPFV GRILDWHVAN TDKKSYEPLE DPGVKSVTKI YNYYKKFSYK TIVMGASFRN TGEIKALAGC DFLTISPKLL GELLQDNAKL VPVLSAKAAQ ASDLEKIHLD EKSFRWLHNE DQMAVEKLSD GIRKFAADAV KLERMLTERM FNAENGK
• Purity: > 90% by SDS – PAGE.
• Form: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: TALDO1 transaldolase 1 [ Homo sapiens ]
• Synonyms: TALDO1; transaldolase 1; TAL; TALH; TAL-H; TALDOR; transaldolase; glycerone transferase; dihydroxyacetone transferase; EC 2.2.1.2;TALDO
• Gene ID: 6888
• mRNA Refseq: NM_006755
• Protein Refseq: NP_006746
• MIM: 602063
• UniProt ID: P37837
• Chromosome Location: 11p15.5-p15.4
• Pathway: Metabolic pathways; Pentose phosphate pathway
• Function: monosaccharide binding; protein binding; transaldolase activity; transferase activity